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Medical Category: Infectious Disease

PRIEST Score rebel em

The PRIEST Score: Predicting Adverse Outcomes in COVID-19

Background: The limited availability of rapid tests with sufficient sensitivity has been an issue since the beginning of the pandemic.  Therefore, multiple clinical decision scores have been studied to overcome this issue. The addition of laboratory and radiological information can …

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Infectious Disease

REBEL Cast Ep100: REVVED UP – COVID-19 Vaccination in the ED

Background: COVID-19 is now a vaccine preventable illness but, unfortunately, many have not received the COVID-19 vaccine due to a number of reasons including access, misinformation and a lack of confidence.  In the US, the emergency department is the safety …

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Infectious Disease

RECOVERY Trial: The REGN-COV Antibody Cocktail in COVID19

Background: Antibodies targeted at the SARS-CoV2 spike protein are an essential part of the body’s immune response to COVID19 infection. Infection with SARS-CoV2 stimulates the immune system to produce a polyclonal spike protein antibody response in the host. Vaccines have …

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Infectious Disease

The SAFER Trial: Pediatric CAP – Amoxicillin 5 days vs 10 days

Background: The evidence supporting the use of a 10-day course of high-dose amoxicillin to treat community-acquired pneumonia (CAP) in pediatric patients is weak. In addition, medicine is trending towards shorter courses of antibiotics when clinically appropriate. REBEL EM covered a similar …

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Infectious DiseaseThoracic and Respiratory

COV-BARRIER: Baricitinib in Hospitalized Adults with COVID19

Background: Outside of vaccines, effective pharmaceuticals for COVID19 continue to be evasive. Steroids have been a success (in patients who require supplemental O2) leading to additional studies investigating optimal drug and dose. Despite early excitement, we’ve seen high-quality studies demonstrate …

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Infectious Disease

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