Archive

Author: Salim Rezaie

The ACORN Trial: Battle of the Gorilla-Cillins (Cefepime vs Piperacillin-Tazobactam)

Background: Acutely ill adults presenting to the hospital with suspected infection commonly receive empiric, broad-spectrum antibiotics as part of their initial management including coverage of both MRSA and pseudomonas species.  MRSA coverage includes the use of vancomycin while anti-pseudomonal coverage …

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Infectious Disease

Intubation in Surgical Patients: VL vs DL

Background: Although most intubations are typically successful there is still a portion of patients that may require multiple intubation attempts.  Repeated intubation attempts could lead to respiratory and hemodynamic complications. We recently covered the DEVICE trial on REBEL EM which …

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Procedures and SkillsResuscitationThoracic and Respiratory

REBEL Cast Ep125: 1st 48 Hours of PE Management – How Good Is Unfractionated Heparin?

Background: The mainstay of treatment for symptomatic pulmonary embolism  (PE) is anticoagulation (AC).  Patients with higher-risk PE may require advanced interventions such as thrombolytic therapy, surgical thrombectomy, or even extracorporeal membrane oxygenation (ECMO). Because of its short half-life and availability …

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CardiovascularHematology and OncologyResuscitationThoracic and Respiratory

REBEL Cast Ep124: Nitrates in Right Sided MIs?

Background: Nitrates can help improve symptoms and ischemia in the setting of acute myocardial infarction. Current teaching holds that nitrates should be avoided in patients with potential right ventricular myocardial infarction (RVMI), due to the risk of decreasing preload and …

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Cardiovascular

Let’s Get Salty: Hypertonic 3% Saline Through Peripheral IVs in Adult Patients with Traumatic Brain Injury

Background: Elevated intracranial pressure in patients with acute brain injury is a neurologic emergency requiring early recognition and early aggressive treatment to prevent progression to cerebral ischemia, brain herniation, and ultimately death.  There are two primary options for treatment in …

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NeurologyTrauma

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