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All Categories
  • All Categories
  • Abdominal and Gastrointestinal
  • Allergy and Immunology
  • Cardiovascular
  • Dermatology
  • EMS and Disaster
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Environmental
  • Ethical and Legal
  • Head, Eye, Ear, Nose, and Throat
  • Hematology and Oncology
  • Human Behavior
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  • Neurology
  • Obstetrics and Gynecology
  • Orthopedics
  • Pediatrics
  • Procedures and Skills
  • Psychiatry/Behavioral Health
  • Renal and Genitourinary
  • Resuscitation
  • Team Performance
  • Thoracic and Respiratory
  • Toxicology
  • Trauma
Ottawa vs Pittsburgh Knee Rules title image comparing knee x-ray decision rules for acute knee injuries.

MDCalc Wars: Ottawa vs Pittsburgh — Which Knee Rule Should You Use?

Not every knee injury needs an x-ray. This post compares the Ottawa and Pittsburgh Knee Rules, highlighting when each rule applies, how they perform, and common pitfalls for ED clinicians.

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Orthopedics

Clinical Conundrum: What Is the Role of TXA in Dysfunctional Uterine Bleeding?

There are a number of accepted treatments for dysfunctional uterine bleeding (DUB) endometrial ablation and hysterectomy as well as medical treatments like hormonal therapy, NSAIDs and tranexamic acid (TXA). The American College of Obstetrics and Gynecology (ACOG) recommends the use ...

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Obstetrics and Gynecology

Systematic Review and Meta-Analysis of Preoxygenation Strategies For Intubation of Critically Ill Patients

What are the differences in efficacy and safety of HFNC, NIPPV, and facemask oxygen for preoxygenation of patients who are critically ill requiring tracheal intubation?

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ResuscitationThoracic and Respiratory
OPTION Trial tenecteplase for non-LVO stroke (late window, CT perfusion selected)

The OPTION Trial: Late-Window TNK for Non-LVO Stroke

The OPTION trial evaluated IV tenecteplase (0.25 mg/kg) in CT perfusion–selected non-LVO ischemic stroke patients treated 4.5–24 hours after last-known-well. Tenecteplase improved excellent 90-day outcomes (mRS 0–1) but increased symptomatic intracranial hemorrhage, with the benefit–harm balance sensitive to outcome and ...

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Neurology

The EVERDAC Trial: Non-Invasive BP vs Arterial Lines in the Critically Ill

The EVERDAC trial sought to determine if managing shock with noninvasive brachial cuff monitoring is noninferior to early (<4 hours) arterial catheter placement

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CardiovascularResuscitation
Growth vs fixed mindset in medicine illustrated by evolving tree heads showing learning, development, and performance improvement in healthcare

REBEL MIND – Growth vs Fixed Mindset in Medicine

Mindset shapes everything we do in medicine—from how we teach and learn to how we show up for patients at the bedside. In this episode, we delve into how the mindset of clinicians can profoundly influence their performance, professional growth, ...

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Human BehaviorPsychiatry/Behavioral HealthTeam Performance
Minimalist comparison graphic of HAT vs SEDAN for estimating hemorrhage risk after stroke thrombolysis, featuring a grayscale brain, red lightning bolt, and labeled comparison circles.

MDCalc Wars: HAT vs SEDAN — Hemorrhage Risk After Stroke Thrombolysis

The HAT and SEDAN scores help estimate symptomatic intracranial hemorrhage risk after stroke thrombolysis. This comparison reviews what each tool measures, when to use them, and the key limitations clinicians should know.

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Neurology
Queen of Hearts playing card on a grayscale deck representing AI vs physicians in STEMI-equivalent and STEMI-mimic ECG interpretation

The Queen of Hearts Returns: AI vs Physicians in STEMI-Equivalent and STEMI-Mimic ECGs

STEMI-equivalent and STEMI-mimic ECGs are among the most difficult tracings to interpret. This study examines how Queen of Hearts AI performed against physicians when accuracy in cath lab activation decisions mattered most.

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Cardiovascular

Clinical Conundrum: Is Acetaminophen Safe in Pregnancy?

In the first trimester, fever is associated with increased risk of birth defects such as cleft lip and palate, as well as serious neural-tube defects such as spina bifida and anencephaly. In late pregnancy, fevers can boost the risk of ...

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Obstetrics and Gynecology

Diastology: Use E/e’ to Estimate Left Atrial Pressure

POCUS diastology doesn’t diagnose chronic diastolic dysfunction—it estimates left atrial pressure in real time. Learn how to capture E and e’ from an apical 4-chamber view, calculate E/e’, and rapidly distinguish cardiogenic pulmonary edema from other causes of acute dyspnea ...

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Procedures and SkillsResuscitation
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