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All Categories
  • All Categories
  • Abdominal and Gastroinstestinal
  • Allergy and Immunology
  • Cardiovascular
  • Dermatology
  • EMS and Disaster
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Environmental
  • Ethical and Legal
  • Head, Eye, Ear, Nose, and Throat
  • Hematology and Oncology
  • Infectious Disease
  • Neurology
  • Obstetrics and Gynecology
  • Orthopedics
  • Pediatrics
  • Procedures and Skills
  • Pyschobehavioral
  • Renal and Genitourinary
  • Resuscitation
  • Thoracic and Respiratory
  • Toxicology
  • Trauma

MDCalc Wars: HEART Score Vs. EDACS

Chest pain is one of the most common—and anxiety-inducing—presentations in the Emergency Department. With millions of visits each year, clinicians face the constant challenge of identifying who is having a major cardiac event and who can safely go home. While ...

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Cardiovascular

Combination Inhalers in Asthma: Time to Switch?

🧭 REBEL Rundown 📌 Key Points 💨 Most asthma patients still leave the ED with a SABA alone—time for an upgrade. 📉 SABA/ICS combo inhalers cut severe exacerbations compared to SABA alone. 🏥 Study excluded typical ED patients—few had recent ...

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Thoracic and Respiratory

REBEL Core Cast 135.0: A Simple Approach to Hypoxemia (vs. Hypoxia)

In this episode, we break down a practical bedside approach to hypoxemia. We clarify the difference between hypoxemia (low oxygen in the blood) and hypoxia (low oxygen at the tissue level), and walk through the major causes of hypoxemia that ...

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ResuscitationThoracic and Respiratory

The ADAPT-Sepsis Trial: Biomarker-Guided Antibiotic Duration for Hospitalized Patients with Suspected Sepsis

Antibiotic stewardship entails delivering the most appropriate antimicrobial therapy for the most appropriate duration of time to help provide the best outcome for patients with sepsis. An unnecessarily extended course of antibiotics leads to adverse effects, greater cost, medication utilization ...

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Infectious Disease

REBEL Core Cast 134.0 – Acetaminophen Toxicity

Acetaminophen (APAP) overdose remains one of the most common causes of acute liver failure in the United States. While its therapeutic use is widespread and generally safe, unintentional overdoses and delayed presentations can lead to devastating outcomes. In this episode ...

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Toxicology

MDCalc Wars: NEXUS Criteria Vs Canadian C-Spine Rules

Over 1 million blunt trauma patients visit US emergency departments each year for possible c-spine injuries. Yet, 98% of c-spine imaging shows no fracture. Using clinical decision tools can safely and significantly reduce unnecessary imaging.

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Trauma

Is 7 Days Enough? Rethinking Antibiotic Duration in Sepsis — The BALANCE Trial

Current IDSA guidelines for sepsis recommend individualized durations of antibiotic therapy based on source control and clinical response, but definitive guidance remains limited. Three small noninferiority RCTs suggested that 7 days of antibiotics may be sufficient for patients with gram-negative ...

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Infectious Disease

TNK vs tPA — The ORIGINAL Trial

The American Heart Association and the European Stroke Organization have updated their guidelines to recommend TNK as an alternative to tPA in patients eligible for thrombolysis. TNK, a bioengineered variant of tPA, has some advantages, including its single-dose administration, fibrin ...

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Neurology

How Accurate are Blood Gas Electrolyte Measurements?

Bottom Line Up Top: Blood gas electrolytes closely correlate with serum measurements and can be used under most circumstances to guide clinical care. Clinical Scenario: A 62 year old woman with a history of HTN, ESRD on MWF dialysis presents ...

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Endocrine, Metabolic, Fluid, and Electrolytes

Size Matters: The Impact of Cuff Size on Blood Pressure

Background: Accurate blood pressure (BP) measurement is essential in the emergency department (ED), where it serves as a key marker of hemodynamic stability and informs critical management decisions. Improper technique and incorrect cuff sizing can lead to falsely high or ...

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Procedures and Skills

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