Archive

Medical Category: Neurology

HINTS vs Sudbury Vertigo Risk Score title graphic featuring a brain and inner-ear illustration.

MDCalc Wars: HINTS vs Sudbury Vertigo Risk Score — Which Tool Fits the Dizzy Patient?

HINTS or the Sudbury Vertigo Risk Score? Learn when to use each tool for the dizzy patient, why patient selection and HINTS training matter, and which pitfalls can lead to missed serious diagnoses.

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Neurology

The A2B Trial: Are Alpha-2 Agonists Better than Propofol for ICU Sedation?

Does primary sedation with dexmedetomidine or clonidine reduce the time to successful extubation in mechanically ventilated critically ill patients compared to propofol-based sedation?

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Neurology

SPICE III Trial: Does Early Dexmedetomidine Improve Survival in Mechanically Ventilated ICU Patients?

Is HFNC as effective as NIV in reducing respiratory rate and improving respiratory distress within 2 hours in ACPE?

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Neurology
OPTION Trial tenecteplase for non-LVO stroke (late window, CT perfusion selected)

The OPTION Trial: Late-Window TNK for Non-LVO Stroke

The OPTION trial evaluated IV tenecteplase (0.25 mg/kg) in CT perfusion–selected non-LVO ischemic stroke patients treated 4.5–24 hours after last-known-well. Tenecteplase improved excellent 90-day outcomes (mRS 0–1) but increased symptomatic intracranial hemorrhage, with the benefit–harm balance sensitive to outcome and ...

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Neurology
Minimalist comparison graphic of HAT vs SEDAN for estimating hemorrhage risk after stroke thrombolysis, featuring a grayscale brain, red lightning bolt, and labeled comparison circles.

MDCalc Wars: HAT vs SEDAN — Hemorrhage Risk After Stroke Thrombolysis

The HAT and SEDAN scores help estimate symptomatic intracranial hemorrhage risk after stroke thrombolysis. This comparison reviews what each tool measures, when to use them, and the key limitations clinicians should know.

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Neurology

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