Archive

Medical Category: Neurology

New and Interesting: Timolol Eyedrops to Treat Migraine Headaches

Background: Acute migraine headaches are a common presentation to emergency departments.  Treatment can be challenging: multiple medications are often required and allergies can limit options. Oral timolol maleate is approved by the FDA for migraine prophylaxis but is not typically ...

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Neurology

Adjunctive Pain Management of Renal Colic and Migraines

Background: Renal colic and migraine headaches are common emergency department presentations.  There are a wide range of medications available to treat pain from these disorders including opioids and non-steroidal anti-inflammatory drugs. Opioids have two major issues: dependency and side effects ...

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NeurologyRenal and Genitourinary

The THALES Trial: Ticagrelor and Aspirin vs Aspirin Alone in Acute Ischemic Stroke or TIA

Background: The risk of a subsequent ischemic stroke in the first few months after an acute ischemic stroke or transient ischemic attack is approximately 5 to 10%. In these patients Aspirin has been used to prevent secondary ischemia, and trials ...

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Neurology

Infectious Acute Transverse Myelitis Secondary to COVID-19

The Coronaviridae family and its genera coronaviruses have been implicated as having neurotropic and neuroinvasive capabilities in human hosts (Bohmwald 2018). They have been associated with the development of neuropsychiatric symptoms, seizure activity, encephalomyelitis, acute flaccid paralysis, cerebral venous sinus ...

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Infectious DiseaseNeurology

Thrombolysis in Acute Ischemic Stroke: Now We Have No Positive RCTs

Background: The scientific process in medicine is complicated. Obtaining high-quality data to guide management requires hypothesis formulation, data to support the hypothesis and study replication. Time and again beneficial findings in therapeutic studies fail to be replicated in subsequent studies. ...

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Neurology

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