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Archive
Medical Category: Neurology
The DEVT + SKIP Trials: Does Systemic Thrombolysis Prior to Endovascular Treatment Improve Outcomes in Large Vessel Occlusion Strokes?
Background: The publication of the MR CLEAN trial in January 2015 changed the face of ischemic stroke care. This was the first study demonstrating a benefit to endovascular treatment of a specific subset of ischemic stroke patients: those with a ...
TIA Risk Stratification: The Canadian TIA Score vs ABCD2
Background: Patients who present with a transient ischemic attack (TIA) are at higher risk of subsequent stroke, especially in the short term (< 7 days). However, the majority of these patients do not experience strokes which leads to a clinical ...
I-FiBH Trial: Intravenous Fluids in Benign Headaches – A Randomised, Single-Blinded Clinical Trial
Background: Headache was the 5th most common reason for patients to present to the emergency department in the US in 2016. Often ED providers include IV fluid boluses in their headache treatment cocktail, with prior research demonstrating IV fluids are ...
Tenecteplase for Thrombolysis of AIS?
Background: Alteplase has been the accepted thrombolytic for acute ischemic stroke (AIS) for 25 years. However, recent data has emerged regarding tenectaplase as an alternative. Tenecteplase is a modified form of alteplase, with a lower cost and more favorable pharmacokinetic ...