Archive

Medical Category: Toxicology

REBEL Cast Ep102: High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder

Background information: Buprenorphine and buprenorphine-containing medications are being used in emergency departments for treatment of patients with opioid use disorder (1). Buprenorphine is a high-affinity partial agonist of the μ-opioid receptor. Buprenorphine has a higher affinity for the μ-opioid receptor …

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Toxicology

Droperidol: Making a Comeback!!!

Background: Droperidol came onto the market in 1967 and, over time, became a frequently employed treatment of headache, nausea, agitation, acute pain, chronic pain, pain in the context of opioid-tolerance and refractory abdominal pain.  Unfortunately, in December 2011, the US …

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Toxicology

REBEL Cast Ep96: Heroin OD – Is a 2-Hour Observation Protocol Long Enough?

Background: Opioid-related emergency department visits have been increasing over the past two decades in correlation with increasing rates of heroin use in the United States. Naloxone, which is used to reverse heroin overdose, has a half-life of approximately 60 to …

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Toxicology

Pearls from ResusX Rewired 2020

From Oct 6th – 8th, 2020, Haney Mallemat (@CriticalCareNow) and his team put on an absolutely amazing online critical care conference called ResusX Rewired.  ResusX is a conference designed by resuscitationists to provide clinicians with the most up to date …

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CardiovascularEndocrine, Metabolic, Fluid, and ElectrolytesInfectious DiseaseProcedures and SkillsResuscitationThoracic and RespiratoryToxicologyTrauma

Topical Capsaicin & Cannabinoid Hyperemesis Syndrome

Background Information: Cannabinoid Hyperemesis Syndrome (CHS) is characterized by the chronic use of cannabis paired with nausea, recurrent vomiting episodes and diffuse abdominal pain.1 The pathophysiology of CHS remains unclear and large systematic reviews of the literature have recommended up to …

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Abdominal and GastroinstestinalToxicology

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