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All Categories
  • All Categories
  • Abdominal and Gastroinstestinal
  • Allergy and Immunology
  • Cardiovascular
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Environmental
  • Ethical and Legal
  • Head, Eye, Ear, Nose, and Throat
  • Hematology and Oncology
  • Infectious Disease
  • Neurology
  • Obstetrics and Gynecology
  • Orthopedics
  • Pediatrics
  • Procedures and Skills
  • Pyschobehavioral
  • Renal and Genitourinary
  • Resuscitation
  • Thoracic and Respiratory
  • Toxicology
  • Trauma

The MENDS2 Trial: Dexmedetomidine vs Propofol for Sedation

Background: In patients requiring mechanical ventilation, sedative medications are used for patient comfort and safety.  However, these medications can also lead to brain dysfunction (i.e. delirium or coma) and long-term cognitive impairment. Currently, the Society of Critical Are Medicine [2] …

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Thoracic and Respiratory

Gone in 120 Seconds!

By the time you finish reading this post, you could have completed most items on your daily to-do list. It’s surprising how many tasks can be completed in under 2 minutes once the next action is clarified.

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The VICTAS Trial: How Many More RCTs do we Need on the Metabolic Cocktail in Sepsis?

Background: Since the publication of the before and after Marik trial [1] published in 2016, there have been six randomized clinical trials trying to answer the question of the utility of the metabolic cocktail (Vitamin C, thiamine, and hydrocortisone) in …

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Infectious Disease

REBEL Core Cast 53.0 – Hypertensive Encephalopathy

Take Home Points Altered mental status has numerous possible etiologies. Splitting it into vital sign issues, toxic/metabolic, infectious processes, CNS issues (bleed, mass) and psych/dementia is a good way to organize your thoughts Hypertensive encephalopathy is a diagnosis of exclusion …

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Cardiovascular

GLUCOCOVID: A Controlled Trial of Methylprednisolone in COVID-19 Pneumonia

Background Information: The use of corticosteroids in patients with pneumonia secondary to COVID-19 has been a controversially hot topic, particularly early on in the pandemic. Prior evidence seen in Severe Acute Respiratory Syndrome (SARS) and Middle Eastern Respiratory Syndrome have …

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Infectious DiseaseThoracic and Respiratory

Delayed Antibiotic Prescriptions for Children: DAP, IAP, vs NAP

Background: Respiratory tract infections (RTIs) are a common reason for medical visits in kids.  Most RTIs are self-limited and the addition of antibiotics rarely alters the course of disease. However, antibiotics are frequently prescribed for these conditions.  Antibiotic overuse is …

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Pediatrics

Data from Israel on the BNT162b2 (Pfizer) mRNA COVID-19 Vaccine

Background: COVID-19 vaccination is ramping up both in the US as well as throughout the world. Randomized clinical trials looking at the efficacy of the mRNA vaccines demonstrated 94% to 95% reductions in symptomatic cases (Polack 2020). Randomized clinical trials …

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Infectious Disease

Systemic Review and Meta Analysis on Topical Pain Control in Corneal Abrasions

 Background Information: Corneal abrasions are responsible for the largest proportion of eye-related chief complaints in patients presenting to emergency departments in the United States. There is substantial variability in physician practice when it comes to pain control. Ophthalmology literature has …

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Head, Eye, Ear, Nose, and Throat

Data from Israel in Health-Care Workers Vaccinated with 1st Dose of the Pfizer COVID-19 Vaccine

Background: Israel has succeeded in ramping up its vaccination program faster than any nation in the world. In December 2020, Israel began a national immunization campaign prioritizing health-care workers. In the original clinical trial data, the Pfizer vaccine was estimated …

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Infectious Disease

Characteristics of EM Malpractice Claims

Background: While we try not to think about it, the spectre of litigation hovers around the house of medicine. Medical malpractice books have been written, physicians have found their niche discussing and writing about it and blogs have been started …

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