November 12, 2020

Background: The well-established, standard treatment for acute appendicitis is surgical appendectomy.  However, recent research has challenged the dominance of the surgical approach in looking at antibiotics alone. The available literature on non-operative treatment of appendicitis (NOTA) has important limitations: exclusion of patients with appendicoliths, small sample size and predominance of open appendectomy over laparoscopic appendectomy. While data on NOTA is intriguing, it is clear that additional studies are needed.

November 6, 2020

Babesiosis

Epidemiology Incidence:
  • Overall annual incidence rose from 0.6 to 0.9 cases per 100,000 in the United States between 2012 and 2015 (Gray 2019)
  • Annual incidence is highest in those between 60-69 years of age (Gray 2019)
Age:
  • Median age is 63 years of age with greater than 89% of cases reported in Caucasian patients (Gray 2019 2010)
Gender:
  • Male to female predominance (Gray 2019)

November 5, 2020

Rocky Mountain Spotted Fever (RMSF)

Epidemiology Incidence:
  • Overall annual incidence rose from 1.7 to 7 cases per million in the United States between 2000 and 2007 (Openshaw 2010)
  • Annual incidence is highest in children aged 5-9 years of age (Amsden 2005)
Age:
  • Median age is 42 years of age with greater than 87% of cases reported in Caucasian patients (Openshaw 2010)
Gender:
  • Slight male to female predominance (Openshaw 2010)

November 4, 2020

Ehrlichiosis

Epidemiology Incidence:
  • Overall annual incidence noted to be 3.2 cases per million in the United States between 2008 and 2012 (Biggs 2016)
  • Highest incidence occurs in those 60-69 years of age (Biggs 2016)
Age:
  • Median age is 55 years of age with 64% of cases reported in Caucasian patients (Heitman 2016)
Gender:
  • Slight male to female predominance (Heitman 2016)

November 3, 2020

Anaplasmosis

Epidemiology Incidence:
  • Overall annual incidence rose from 1.4 to 6.1 cases per million in the United States between 2000 and 2010 (Ismail 2017)
  • In endemic areas, the incidence rate is suggested to be more than 50 cases per 100,000 (Ismail 2017)
Age:
  • Median age is 51 years of age with greater than 95% of cases reported in Caucasian patients (Ismail 2017)
Gender:
  • Slight male to female predominance (Demma 2006)
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