Archive

Medical Category: Infectious Disease

REBEL Cast Ep95: Colchicine in COVID (COLCORONA)? Don’t Believe the Hype.

Background: Science by press release. Not the way any of us would choose to operate but, the COVID pandemic has made this a reality. It’s vital that we understand that while pharmaceutical companies have a responsibility to release this information, …

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Infectious Disease

The RECOVERY Trial: Tocilizumab

Background: Publication of the RECOVERY trial results on Dexamethasone were game changing – the drug had a clear reduction in mortality in patients requiring oxygen. Since then, we have had little to celebrate in terms of therapeutics in those with …

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Infectious Disease

BLAZE-1 Final Publication: Monoclonal Antibody Cocktail Part II

Background: One of the many massive challenges of the COVID19 pandemic has been the lack of targeted therapeutics. Extensive efforts have been invested into research with only glimmers of benefit for most drugs. The exception to this has been dexamethasone …

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Infectious Disease

COVID-19 Awake Proning – All Hype?

Background: Facilities around the world have seen surges of COVID-19 pneumonia  patients who have required protracted hospitalizations leading to overwhelmed hospital systems. Awake proning is a practice that was adopted early in the pandemic as a means to avoid, or …

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Infectious DiseaseThoracic and Respiratory

No Evidence that REGN-COV2 (Regeneron) Antibody Cocktail Has Clinical Benefits

Background: Antibodies targeted at the SARS-CoV2 spike protein are an essential part of the body’s immune response to COVID19 infection. The recent emergency use authorization (EUA) Pfizer and Moderna vaccines act by introducing mRNA into the body that instructs cells …

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Infectious Disease

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