Background: Tramadol is a centrally acting synthetic opioid analgesic approved for use in the United States in 1995 by the Food and Drug Administration. In 2014, the Drug Enforcement Agency classified tramadol as a Schedule IV controlled substance. ~41 million …
Background: Epinephrine (adrenaline) has been used in advanced life support in cardiac arrest since the early 1960s. Despite the routine recommendation for its use, evidence to support administration is less than ideal. Â Although it is clear from multiple observational studies …
Background: Convulsive status epilepticus is the most common pediatric neurological emergency worldwide. Currently, phenytoin (UK & Europe) or fosphenytoin (USA) is the recommended second-line IV anticonvulsant for the treatment of pediatric status epilepticus. Some evidence and providers however suggest that …
Normal saline started being used based on work done in the 1830s with cholera. We are still doing the same thing the same way and it’s not until recently we have begun to ask the hard questions about why we …
Background:Â Unwarranted use of antibiotics has several deleterious effects which include, antimicrobial resistance, wasted resources, adverse effects, negative affect on the microbiome of patients, and distracts from potentially more effective interventions. There has recently been a huge push for tests such …
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