The Novel Coronavirus 2019, was first reported on in Wuhan, China in late December 2019.  The outbreak was declared a public health emergency of international concern in January 2020 and on March 11th, 2020, the outbreak was declared a global pandemic.  The spread of this virus is now global with lots of media attention.  The virus has been named SARS-CoV-2 and the disease it causes has become known as coronavirus disease 2019 (COVID-19). This new outbreak has been producing lots of hysteria and false truths being spread, however the data surrounding the biology, epidemiology, and clinical characteristics are growing daily, making this a moving target.

REBEL COVID-19

will serve as a summary of what is currently known, how to screen, when to test, and how to prevent spread, and any new data/information on COVID-19.

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  • REBEL Covid-19
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  • REBEL Covid-19

Awake Proning for COVID-19 Acute Hypoxemic Respiratory Failure

Background: Awake prone positioning was an intervention adopted early in the COVID-19 pandemic for patients with hypoxemic respiratory failure.  Unfortunately, many early trials were not powered to show improvements in oxygenation, escalation of respiratory support, or mortality. The one meta-analysis …

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ResuscitationThoracic and Respiratory

It’s All About Risk: BNT162b2 mRNA COVID-19 Vaccination vs Natural Infection

Background: The world has been involved in mass vaccination efforts for the last nine months. Since the vaccines were approved, billions of doses have been administered.  Initial trials showed the COVID-19 vaccines to be efficacious and safe.   However, assessing vaccine …

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Infectious Disease

RECOVERY RS: CPAP vs HFNO vs Conventional Oxygen Therapy in COVID-19

Background: Much of the last two years has been both a complete blur and indelibly memorable. This dichotomy is encapsulated by the rapid changes and updates in medical management and hospital algorithms coupled with the memories of frightened faces of …

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Thoracic and Respiratory

Rebellion21: Good Vibrations with Corona – Using POCUS in the COVID Era via Eric Chin, MD

In this 18-minute presentation from Rebellion in EM 2021, Dr. Eric Chin, MD describes the role of point-of-care ultrasound in the evaluation of a COVID patient. Much of this talk focuses on thoracic and lung ultrasound.

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Infectious DiseaseProcedures and SkillsThoracic and Respiratory
PRIEST Score rebel em

The PRIEST Score: Predicting Adverse Outcomes in COVID-19

Background: The limited availability of rapid tests with sufficient sensitivity has been an issue since the beginning of the pandemic.  Therefore, multiple clinical decision scores have been studied to overcome this issue. The addition of laboratory and radiological information can …

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Infectious Disease

COVID-19 and Anticoagulation: Full Dose or Prophylactic Dose?

Background: Patients with COVID-19 are at a high risk for the development of venous thromboembolic disease [Link is HERE]. Alveolar capillary microthrombi appear to be 9x more prevalent in patients with COVID-19 compared to H1N1. As a result, enhanced-dose anticoagulation …

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Hematology and Oncology

RECOVERY Trial: The REGN-COV Antibody Cocktail in COVID19

Background: Antibodies targeted at the SARS-CoV2 spike protein are an essential part of the body’s immune response to COVID19 infection. Infection with SARS-CoV2 stimulates the immune system to produce a polyclonal spike protein antibody response in the host. Vaccines have …

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Infectious Disease

COV-BARRIER: Baricitinib in Hospitalized Adults with COVID19

Background: Outside of vaccines, effective pharmaceuticals for COVID19 continue to be evasive. Steroids have been a success (in patients who require supplemental O2) leading to additional studies investigating optimal drug and dose. Despite early excitement, we’ve seen high-quality studies demonstrate …

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Infectious Disease

From Emergency Medicine to Hostage Negotiation

Earlier this year, my home shop began administering the Johnson & Johnson COVID-19 vaccine to patients in the emergency department (ED). Thirteen years of experience in emergency medicine has afforded me many opportunities to counsel patients on lifestyle modifications, death …

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Infectious Disease

LIVE-AIR Trial: What the Heck is Lenzilumab?

Background: We have all seen the wide spectrum of illness caused by COVID-19 ranging from asymptomatic disease on one extreme all the way up to critical illness, acute respiratory disease and ultimately death at the other extreme.  In the most …

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Infectious Disease

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