The Novel Coronavirus 2019, was first reported on in Wuhan, China in late December 2019.  The outbreak was declared a public health emergency of international concern in January 2020 and on March 11th, 2020, the outbreak was declared a global pandemic.  The spread of this virus is now global with lots of media attention.  The virus has been named SARS-CoV-2 and the disease it causes has become known as coronavirus disease 2019 (COVID-19). This new outbreak has been producing lots of hysteria and false truths being spread, however the data surrounding the biology, epidemiology, and clinical characteristics are growing daily, making this a moving target.

REBEL COVID-19

will serve as a summary of what is currently known, how to screen, when to test, and how to prevent spread, and any new data/information on COVID-19.

  • All Categories
  • Cardiovascular
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Hematology and Oncology
  • Infectious Disease
  • Neurology
  • Pediatrics
  • Procedures and Skills
  • Resuscitation
  • Thoracic and Respiratory
All Categories
  • All Categories
  • Cardiovascular
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Hematology and Oncology
  • Infectious Disease
  • Neurology
  • Pediatrics
  • Procedures and Skills
  • Resuscitation
  • Thoracic and Respiratory

COVID-19 and Anticoagulation: Full Dose or Prophylactic Dose?

Background: Patients with COVID-19 are at a high risk for the development of venous thromboembolic disease [Link is HERE]. Alveolar capillary microthrombi appear to be 9x more prevalent in patients with COVID-19 compared to H1N1. As a result, enhanced-dose anticoagulation …

Read More
Hematology and Oncology

RECOVERY Trial: The REGN-COV Antibody Cocktail in COVID19

Background: Antibodies targeted at the SARS-CoV2 spike protein are an essential part of the body’s immune response to COVID19 infection. Infection with SARS-CoV2 stimulates the immune system to produce a polyclonal spike protein antibody response in the host. Vaccines have …

Read More
Infectious Disease

COV-BARRIER: Baricitinib in Hospitalized Adults with COVID19

Background: Outside of vaccines, effective pharmaceuticals for COVID19 continue to be evasive. Steroids have been a success (in patients who require supplemental O2) leading to additional studies investigating optimal drug and dose. Despite early excitement, we’ve seen high-quality studies demonstrate …

Read More
Infectious Disease

From Emergency Medicine to Hostage Negotiation

Earlier this year, my home shop began administering the Johnson & Johnson COVID-19 vaccine to patients in the emergency department (ED). Thirteen years of experience in emergency medicine has afforded me many opportunities to counsel patients on lifestyle modifications, death …

Read More
Infectious Disease

LIVE-AIR Trial: What the Heck is Lenzilumab?

Background: We have all seen the wide spectrum of illness caused by COVID-19 ranging from asymptomatic disease on one extreme all the way up to critical illness, acute respiratory disease and ultimately death at the other extreme.  In the most …

Read More
Infectious Disease

Dexamethasone vs Methylprednisolone in ICU Patients with COVID19

Background Information: Over one year into the pandemic many therapies to treat COVID-19 have targeted innumerable aspects of the virus. Most recently, the use of corticosteroids to treat the virus’ excessive inflammatory effects has become the front and center of …

Read More
Endocrine, Metabolic, Fluid, and ElectrolytesInfectious DiseaseThoracic and Respiratory

GLUCOCOVID: A Controlled Trial of Methylprednisolone in COVID-19 Pneumonia

Background Information: The use of corticosteroids in patients with pneumonia secondary to COVID-19 has been a controversially hot topic, particularly early on in the pandemic. Prior evidence seen in Severe Acute Respiratory Syndrome (SARS) and Middle Eastern Respiratory Syndrome have …

Read More
Infectious DiseaseThoracic and Respiratory

Data from Israel on the BNT162b2 (Pfizer) mRNA COVID-19 Vaccine

Background: COVID-19 vaccination is ramping up both in the US as well as throughout the world. Randomized clinical trials looking at the efficacy of the mRNA vaccines demonstrated 94% to 95% reductions in symptomatic cases (Polack 2020). Randomized clinical trials …

Read More
Infectious Disease

Data from Israel in Health-Care Workers Vaccinated with 1st Dose of the Pfizer COVID-19 Vaccine

Background: Israel has succeeded in ramping up its vaccination program faster than any nation in the world. In December 2020, Israel began a national immunization campaign prioritizing health-care workers. In the original clinical trial data, the Pfizer vaccine was estimated …

Read More
Infectious Disease

Be Heard In a Respirator Mask

Background: A major challenge during the COVID pandemic is balancing personal protection and communication. Being heard while wearing a surgical mask or N95 isn’t too much of a challenge, communication can be significantly impaired while wearing a respirator mask. There …

Read More
Resuscitation

Sponsored