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Medical Category: Endocrine, Metabolic, Fluid, and Electrolytes

Intermittent Fasting and PLEASE Don’t Just Read the Abstract

Background: There are many lifestyle modification strategies available as a way to aid in weight management.  Two in particular include calorie restriction and intermittent fasting. Caloric restriction is self-explanatory, however personal experience has been it can be difficult to maintain …

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Endocrine, Metabolic, Fluid, and Electrolytes

REBEL Cast Ep108: The PLUS Trial – Balanced vs Unbalanced Fluids in the Critically Ill

Background: In the past few years there has been a growing debate between  the use of balanced multielectrolyte solutions (BMES) and saline in the critically ill (See the “for more about this topic” section below). Recent research has yielded inconsistent …

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Endocrine, Metabolic, Fluid, and Electrolytes

SCOPE-DKA: Normal Saline vs Plasmalyte in Severe DKA

Background Information:  Diabetic Ketoacidosis (DKA) is a life-threatening complication of diabetes that we frequently encounter in both the emergency department (ED) and intensive care unit (ICU). While intravenous fluid replacement remains one of several cornerstones of therapies, much debate exists …

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Endocrine, Metabolic, Fluid, and ElectrolytesResuscitation

REBEL Core Cast 63.0 – Adrenal Crisis

Take Home Points Adrenal insufficiency is a life-threatening emergency; recognize early and treat aggressively Hallmark is hypotension refractory to IVF/pressors Suspect in patients with unexplained hypotension and risk factors Prior glucocorticoid therapy History of autoimmune diseases Hyperpigmentation  AIDS or TB …

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Endocrine, Metabolic, Fluid, and Electrolytes

The BaSICS Trial – Balanced Solution vs 0.9% Saline Solution in Critically Ill Patients

Background: One of the most common treatments in critically ill patients is  the administration of intravenous fluids.  Historically, 0.9% saline has been one of the most common solutions used in resuscitation. In 2015 we saw the publication of the SPLIT …

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Endocrine, Metabolic, Fluid, and Electrolytes

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