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The PACER Trial: Platelet Transfusion before CVC Placement in Patients with Thrombocytopenia

Background: Bleeding complications are an uncommon but potentially a significant risk during central venous catheter (CVC) placement. Thrombocytopenia is associated with increased bleeding complications but there is no good-quality evidence showing that prophylactic platelet transfusions decrease that risk. Previous studies ...

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Hematology and OncologyProcedures and Skills

REBEL Core Cast 107.0 – Vertebral Osteomyelitis

Take Home Points Clinical presentation is very nonspecific; evaluate all patients presenting with back pain for infectious risk factors. Baseline labs should not guide diagnosis, but may assist in later management. MRI is key to diagnosis, obtain this imaging in ...

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Infectious DiseaseOrthopedics

Clinical Conundrum: Does IM Ketorolac Provide Superior Pain Relief to PO Ibuprofen?

Clinical Scenario: A 34-year-old woman presents to the ED with back pain. After your history and physical, you conclude that the patient’s pain is muscular in origin and likely secondary to heavy lifting while moving apartments. You contemplate analgesic options ...

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Trauma

Back in the Game: The Effects of Activity on Youth Concussion Recovery

Background: Sports-related concussions are among the most common injuries in children and adolescents, affecting millions of youth athletes annually.1 Given their prevalence in this population, providers must be up to date on diagnosis and management. Historical practice recommends rest to ...

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Pediatrics

TAME Trial: Mild Hypercapnia vs Normocapnia in Out-of-Hospital Cardiac Arrest

Background Information: Cardiac arrest is a devastating event that imposes considerable human and financial burdens. While it is widely recognized that cardiac arrest leads to brain injury, what is often overlooked is the persistent cerebral hypoperfusion that continues even after ...

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CardiovascularResuscitation
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