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Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia (MINT Trial)

Background: Concurrent anemia worsens outcomes in patients that present with acute myocardial infarctions. Transfusions increase the oxygen carrying capacity of blood which can improve the perfusion of at-risk cardiac tissue. However, transfusions are also associated with immunosuppression, thrombotic phenomena, volume …

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CardiovascularHematology and Oncology

REBEL Core Cast 118.0 – IM vs PO NSAIDs

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Another Study on Peripheral Vasopressors

Background: Use of vasopressors is a common practice to support hemodynamics and optimization of tissue perfusion in patients presenting with shock.  Historically the administration of vasopressors was restricted to central venous catheters (CVC) due to concerns for local tissue injury …

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Resuscitation

The NICO Trial: NIV in Comatose Patients with Acute Poisoning

Background:  Patients with decreased level of consciousness due to alcohol, drugs, or medications commonly present to the ED. These patients can be at risk of vomiting and aspiration and often prompts clinicians to pursue definitive airway management to avoid pneumonia …

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ResuscitationToxicology

Clinical Conundrums: Do We Need to Order a CT for Every Patient with Renal Colic?

Bottom Line Up Top: In selective patients presenting with flank pain, we can diagnose renal colic without a CT scan. There is also a subset of patients that would benefit from IV contrast enhanced CT scanning. Clinical Scenario: A 35-year-old …

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Renal and Genitourinary

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