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Nirmatrelvir for Vaccinated or Unvaccinated Adult Outpatients with COVID-19

Background: The clinical burden of severe COVID-19 triggered a pharmaceutical race to find effective, easily accessible, oral treatments that could decrease the morbidity and mortality associated with the disease. Nirmatrelvir is an oral antiviral agent that inhibits the SARS-CoV2 main ...

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Infectious Disease

Remote Consult Protocols for Retinal Artery Occlusion: A Visionary Approach in Emergency Care?

Background:  Retinal artery occlusion (RAO) is a time-sensitive ophthalmic emergency that demands rapid diagnosis and intervention. Administration of intravenous tissue plasminogen activator (IVtPA) within 4.5 hours of symptom onset appears to be the most promising approach for improving visual outcomes, supported ...

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Head, Eye, Ear, Nose, and Throat

The PROTECTION Trial – A Randomized Trial of Intravenous Amino Acids for Kidney Protection

Background Information: Acute kidney injury (AKI) is one of the most frequent complications of cardiac surgery and the cause is complex. Renal hypoperfusion from decreased glomerular filtration rate after cardiopulmonary bypass is a major contributor.1 This in combination with exogenous ...

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CardiovascularRenal and GenitourinaryResuscitation

The REBEL Lit Distillery at ResusX

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A Winning Hand in Cardiology: Queen of Hearts AI Model Enhances OMI Detection

Background: Cath lab activation based on ST-elevation myocardial infarction (STEMI) criteria is founded on aging data and requires evolution. In the “Occlusive Myocardial Infarction (OMI) Manifesto,” emergency physicians Dr. Steve Smith, Dr. Pendell Meyers, and Dr. Scott Weingart introduced a ...

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Cardiovascular

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