Background Information: It is well documented throughout the literature that critically ill patients admitted to the intensive care unit (ICU) with acute kidney injury have a higher morbidity and mortality.1–4 Acute kidney injury may be complicated by acidosis, hyperkalemia and ...
Background: The most severe SARS-CoV-2 infections result in an intense inflammatory response which can lead to acute lung injury and/or acute respiratory distress syndrome. Theoretically, potential treatments for severe disease should have anti-inflammatory action without substantial side effects. One candidate ...
Background: Patients coming to the ED frequently have several interventions performed in their evaluation and management. Blood draws, for the most part, are venous. Occasionally, however, arterial sampling is used to gauge acid-base status, PaO2, PaCO2, lactate etc. This is ...
Background: As the COVID-19 pandemic continues a number of challenges have arisen. Amongst these is the ability of clinicians to predict which patients will suffer from early decompensation. It is well established that there are patients that will rapidly decline ...
Background Information: The care and management of patients with acute respiratory distress syndrome (ARDS) is complex and follows an inciting injury to the lungs. This constellation of symptoms is characterized by hypoxemia, diffuse lung inflammation, decreased lung compliance and noncardiogenic ...
What is it HLH? Hemophagocytic Lymphohistiocytosis (HLH) is a rare and often fatal syndrome of uncontrolled and ineffective inflammatory response to a certain trigger. It is characterized by excessive proliferation of lymphocytes and macrophages (histiocytes), hence the name “lymphohistiocytosis”. This ...
Background: The scientific process in medicine is complicated. Obtaining high-quality data to guide management requires hypothesis formulation, data to support the hypothesis and study replication. Time and again beneficial findings in therapeutic studies fail to be replicated in subsequent studies. ...
Background: Trauma remains the leading cause of death in the United States for those aged less than 45 years old. Those who arrest from hemorrhage or other traumatic mechanism often carry a very poor prognosis. Various studies have placed the ...
Take Home Points Spinal Epidural Abscess may present insidiously and patients often lack the classic triad of fever, back pain and neurologic symptoms Empiric Antibiotics should cover Staphylococcus (including MRSA) and Gram negative Bacilli All patients with clinical suspicion require ...
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