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All Categories
  • All Categories
  • Abdominal and Gastrointestinal
  • Allergy and Immunology
  • Cardiovascular
  • Dermatology
  • EMS and Disaster
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Environmental
  • Ethical and Legal
  • Head, Eye, Ear, Nose, and Throat
  • Hematology and Oncology
  • Human Behavior
  • Infectious Disease
  • Neurology
  • Obstetrics and Gynecology
  • Orthopedics
  • Pediatrics
  • Procedures and Skills
  • Psychiatry/Behavioral Health
  • Renal and Genitourinary
  • Resuscitation
  • Team Performance
  • Thoracic and Respiratory
  • Toxicology
  • Trauma

The ORANGES Trial: Why You Can’t Just Read the Abstract

Background: The cornerstones of sepsis management continues to include early identification, early appropriate empiric antibiotics, definitive source control, and vasopressors to support end organ perfusion. There have been multiple studies looking at the co-administration of hydrocortisone, ascorbic acid, and thiamine ...

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Infectious Disease

Haloperidol for Treatment of Headache in the Emergency Department

Background Information: Headache is a common chief complaint that emergency physicians encounter almost every day and sometimes multiple times in each shift. In fact, headache is the fifth leading cause of patients presenting to the emergency department (ED).1 Current first-line ...

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Neurology

RAFF2: Electrical vs Pharmacological Cardioversion for ED Patients with Acute Atrial Fibrillation

Background: Acute atrial fibrillation (AF) is one of the most common dysrhythmias seen in the emergency department (ED). There has been extensive discussion and debate about the best way to manage acute AF centered around rate and rhythm control.  However, ...

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Cardiovascular

REBEL Core Cast 36.0 – Seizures

Take Home Points When approaching the patient with uspected seizure, focus on questions that matter in determining if the event was a seizure or not Extensive lab work after a first time seizure is not necessary in patients who are ...

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Neurology

COVID-19 Treatment Update: Can We Just Stop Wasting Time on Hydroxychloroquine

Background: Hydroxychloroquine (HCQ) is an antimalarial and immunomodulatory drug that is postulated to exert an antiviral effect by increasing intracellular pH resulting in decreased viral binding at the ACE2 receptor. Azithromycin is a macrolide antibiotic that also has anti-inflammatory and ...

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Infectious Disease

ISAR-REACT 5 Trial: Ticagrelor vs Prasugrel in ACS

Background: In patients presenting to the ED with acute coronary syndrome (ACS), dual antiplatelet therapy is the current standard treatment.  This typically consists of aspirin and an adenosine diphosphate receptor antagonist.  It is fairly well understood that prasugrel and ticagrelor ...

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Cardiovascular

The LOCO2 Trial: Liberal or Conservative Oxygen Therapy for Acute Respiratory Distress Syndrome

Background: In patients with acute respiratory distress syndrome (ARDS) the National Heart, Lung, and Blood Institute ARDS clinical trials network recommends a target partial pressure of arterial oxygen (Pao2) between 55 and 80 mmHg. Goals of arterial oxygenation are not based ...

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Thoracic and Respiratory

REBEL Cast Ep85: The HALT-IT Trial – TXA in Acute GI Bleeds

Background: Acute gastrointestinal bleeding (GIB) is a common diagnosis dealt with by emergency clinicians.  Definitive therapy for acute GIB often includes endoscopy or surgery. However, there is a myriad of pharmaceutical options (i.e. PPI, Somatostatin Analogues, Antibiotics, etc.) as well ...

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Abdominal and Gastrointestinal

Spinal Epidural Abscess (SEA)

Definition: Suppurative infection enclosed within the epidural space Epidemiology Incidence: 2-3 cases per 10,000 hospitalized patients (Sendi 2008). Rate is increasing given the rise in number of spinal procedures and anesthesia techniques Mortality is low at 5%, however, if untreated ...

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Infectious DiseaseNeurology

REBEL Core Cast 35.0 – Environmental Hyperthermia

Take Home Points Heat stroke is a life-threatening disorder characterized by elevated core temperature, compromise to neurologic function and multi-system organ dysfunction The keystone of treatment is rapid cooling within 30 minutes of presentation preferably with ice water immersion Patients ...

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Environmental
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