• All Categories
  • Abdominal and Gastrointestinal
  • Allergy and Immunology
  • Cardiovascular
  • Dermatology
  • EMS and Disaster
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Environmental
  • Ethical and Legal
  • Head, Eye, Ear, Nose, and Throat
  • Hematology and Oncology
  • Human Behavior
  • Infectious Disease
  • Neurology
  • Obstetrics and Gynecology
  • Orthopedics
  • Pediatrics
  • Procedures and Skills
  • Psychiatry/Behavioral Health
  • Renal and Genitourinary
  • Resuscitation
  • Team Performance
  • Thoracic and Respiratory
  • Toxicology
  • Trauma
All Categories
  • All Categories
  • Abdominal and Gastrointestinal
  • Allergy and Immunology
  • Cardiovascular
  • Dermatology
  • EMS and Disaster
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Environmental
  • Ethical and Legal
  • Head, Eye, Ear, Nose, and Throat
  • Hematology and Oncology
  • Human Behavior
  • Infectious Disease
  • Neurology
  • Obstetrics and Gynecology
  • Orthopedics
  • Pediatrics
  • Procedures and Skills
  • Psychiatry/Behavioral Health
  • Renal and Genitourinary
  • Resuscitation
  • Team Performance
  • Thoracic and Respiratory
  • Toxicology
  • Trauma

The ATESS Trial: Time to Let Go of the Metabolic Cocktail

Background: The only well-established treatments for sepsis and septic shock are antibiotic therapy and source control.  Septic shock, the most severe form of sepsis, is characterized by circulatory and cellular metabolism abnormalities.  There have been a host of randomized controlled ...

Read More
Infectious Disease

Pearls from ResusX Rewired 2020

From Oct 6th – 8th, 2020, Haney Mallemat (@CriticalCareNow) and his team put on an absolutely amazing online critical care conference called ResusX Rewired.  ResusX is a conference designed by resuscitationists to provide clinicians with the most up to date ...

Read More
CardiovascularEndocrine, Metabolic, Fluid, and ElectrolytesInfectious DiseaseProcedures and SkillsResuscitationThoracic and RespiratoryToxicologyTrauma

The DIFOCCULT Trial: Time to Change from STEMI/NSTEMI to OMI/NOMI?

Background: Prior to the discovery of thrombolytics, clinicians could only observe their patients completing their myocardial infarctions and then classify them according to whether their subsequent ECGs developed Q waves. When trials showed a clear survival benefit with thrombolytics (especially ...

Read More
Cardiovascular

Out-Of-Hospital TXA for TBI

Background: The CRASH-2 trial, published in 2010, showed a survival benefit for patients with traumatic hemorrhage who received TXA compared to placebo.  TXA has become standard practice in many settings as a result of this data. However, patients with significant ...

Read More
Trauma

REBEL Cast Ep87: Video Laryngoscopy – Standard vs Hyperangulated Geometry

Background information: There are two popular blade shapes for video laryngoscopy, a standard-geometry blade comparable to a Macintosh blade and a hyperangulated blade. The standard-geometry blade permits both direct and indirect visualization during intubation, whereas the hyperangulated blade permits only ...

Read More
Procedures and SkillsResuscitation

Topical Capsaicin & Cannabinoid Hyperemesis Syndrome

Background Information: Cannabinoid Hyperemesis Syndrome (CHS) is characterized by the chronic use of cannabis paired with nausea, recurrent vomiting episodes and diffuse abdominal pain.1 The pathophysiology of CHS remains unclear and large systematic reviews of the literature have recommended up to ...

Read More
Abdominal and GastrointestinalToxicology

REBEL Core Cast 41.0 – Acute Chest Syndrome

Take Home Points 100k people in US have sickle cell, the majority will at some point develop acute chest syndrome (ACS) The mortality rate per episode is 3-9%, similar to those of STEMI ACS is a syndrome – CXR infiltrate ...

Read More
CardiovascularHematology and Oncology

The SWIFFT Trial: To Cut or To Cast – That Is the Question

Background: FOOSH injuries, or falls onto outstretched hands, are a common presentation to the emergency department, and can frequently result in scaphoid fractures.  In fact, scaphoid fractures “account for 90% of all carpal fractures and 2-7% of all fractures” (Dias).  The ...

Read More
Orthopedics

US Expanded Access Program: Convalescent Plasma, Mortality, and COVID-19

Background: Convalescent plasma therapy (CPT) is not a novel treatment modality.  It has been used in other illnesses such as SARS, MERS, and Ebola with variable results. The theory behind CPT is to take antibody rich blood from patients who ...

Read More
Infectious Disease

The ALIC4E Trial: Oseltamivir + Usual Care vs Usual Care Alone

Background: Previous evidence has found that oseltamivir reduces median time to alleviation of influenza symptoms over placebo by about 1 day.  The benefits were greater when treatment was initiated within 24 to 48 hours of symptoms onset. Many previous trials ...

Read More
Infectious Disease
Showing Slide 1 of 11
Get new posts (free)

1 email per week. No spam.

Sponsored