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All Categories
  • All Categories
  • Abdominal and Gastrointestinal
  • Allergy and Immunology
  • Cardiovascular
  • Dermatology
  • EMS and Disaster
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Environmental
  • Ethical and Legal
  • Head, Eye, Ear, Nose, and Throat
  • Hematology and Oncology
  • Human Behavior
  • Infectious Disease
  • Neurology
  • Obstetrics and Gynecology
  • Orthopedics
  • Pediatrics
  • Procedures and Skills
  • Psychiatry/Behavioral Health
  • Renal and Genitourinary
  • Resuscitation
  • Team Performance
  • Thoracic and Respiratory
  • Toxicology
  • Trauma

New and Interesting: Timolol Eyedrops to Treat Migraine Headaches

Background: Acute migraine headaches are a common presentation to emergency departments.  Treatment can be challenging: multiple medications are often required and allergies can limit options. Oral timolol maleate is approved by the FDA for migraine prophylaxis but is not typically ...

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Neurology

The ISARIC WHO Clinical Characterization Protocol: Risk Stratification of Patients Admitted to Hospital with COVID-19

Background: SARS-CoV-2 infection has resulted in a high mortality rate, with the majority of deaths resulting from respiratory failure. As waves of the pandemic continue to overwhelm healthcare systems throughout the world, a pragmatic risk stratification tool that would allow ...

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Infectious Disease

COVID-19 Update: The PlasmAr Trial – Convalescent Plasma vs Placebo

Background: Despite limited high-quality evidence, many institutions are currently using convalescent plasma therapy (CPT) in the treatment of COVID-19.  The majority of the evidence for CPT comes from observational studies lacking placebo arms (US Expanded Access Program). Convalescent plasma therapy ...

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Infectious Disease

BLAZE-1: COVID-19 Neutralizing Antibody (Bamlanivimab)

Background: Throughout the COVID19 pandemic, massive efforts have been invested on the research of effective therapeutics.  Much of the research looks at repurposing older treatments (i.e. antimalarial drugs, antiviral agents, interleukin blockers and convalescent plasma therapy).  There have been no ...

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Infectious Disease

Aromatherapy vs Oral Ondansetron for Antiemetic Therapy Among Adult Emergency Department Patients

Background Information: Nausea and/or vomiting are chief complaints that account over 4 million emergency department (ED) visits each year.1 Multiple studies have shown aromatherapy in the form of isopropyl alcohol “prep” pads to be effective in postoperative nausea and vomiting.2,3 ...

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Abdominal and Gastrointestinal

REBEL Core Cast 45.0 – Mesenteric Ischemia

Take Home Points Be sure to consider mesenteric ischemia in any elderly patient with abdominal pain or lower gastrointestinal (GI) complaints.  Remember, the presentation can be tricky to find and they may have a reassuring abdominal exam. Ask about artherosclerotic ...

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Abdominal and Gastrointestinal

Vexed on Vaccines: Vaccine Hesitancy, Fact Immunity, and a Pandemic of Misinformation

It is no secret we are in the middle of a pandemic, the likes of which our generation has never seen. Every day, clinicians care for thousands of patients infected with SARS-CoV2. One sick person can infect many more without ...

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Infectious Disease

Adjunctive Pain Management of Renal Colic and Migraines

Background: Renal colic and migraine headaches are common emergency department presentations.  There are a wide range of medications available to treat pain from these disorders including opioids and non-steroidal anti-inflammatory drugs. Opioids have two major issues: dependency and side effects ...

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NeurologyRenal and Genitourinary

COVID-19 Update: An Interesting Study on Serotonin Antagonism

Background: We have tried to decrease the number of updates on COVID-19, as I am sure everyone is getting tired of all the trials coming out on this.  I know I am exhausted just reading through everything.  However, every so ...

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Infectious Disease

IM Administration of Tranexamic Acid

Background: We have covered tranexamic acid (TXA) on this blog in several posts. Its use has been studied for everything that bleeds from abnormal uterine bleeding to GI hemorrhage and from multisystem trauma to intracranial hemorrhage. While over the past few ...

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Trauma
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