Archive

Author: Cara Borelli DO

REBEL Cast Ep115 – Phenobarbital vs Lorazepam in Alcohol Withdrawal

Background information: Alcohol has potentiating effects on the inhibitory GABA neurotransmission system and inhibitory effects on the excitatory glutamate neurotransmission system. Chronic alcohol use causes changes to preserve homeostasis, and when the stimulus is removed, alcohol withdrawal results due to ...

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Toxicology

REBEL Cast Ep102: High-Dose Buprenorphine Induction in the Emergency Department for Treatment of Opioid Use Disorder

Background information: Buprenorphine and buprenorphine-containing medications are being used in emergency departments for treatment of patients with opioid use disorder (1). Buprenorphine is a high-affinity partial agonist of the μ-opioid receptor. Buprenorphine has a higher affinity for the μ-opioid receptor ...

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Toxicology

REBEL Cast Ep96: Heroin OD – Is a 2-Hour Observation Protocol Long Enough?

Background: Opioid-related emergency department visits have been increasing over the past two decades in correlation with increasing rates of heroin use in the United States. Naloxone, which is used to reverse heroin overdose, has a half-life of approximately 60 to ...

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Toxicology

REBEL Cast Ep87: Video Laryngoscopy – Standard vs Hyperangulated Geometry

Background information: There are two popular blade shapes for video laryngoscopy, a standard-geometry blade comparable to a Macintosh blade and a hyperangulated blade. The standard-geometry blade permits both direct and indirect visualization during intubation, whereas the hyperangulated blade permits only ...

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Procedures and SkillsResuscitation

E-Cigarette or Vaping Product Use-Associated Lung Injury (EVALI)

Background: Electronic cigarette use, or vaping, has been rising in popularity in the United States. Electronic cigarette use has been associated with respiratory symptoms that have collectively been labeled e-cigarette or vaping product use-associated lung injury (EVALI). In a recent ...

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Thoracic and RespiratoryToxicology

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