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All Categories
  • All Categories
  • Abdominal and Gastrointestinal
  • Allergy and Immunology
  • Cardiovascular
  • Dermatology
  • EMS and Disaster
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Environmental
  • Ethical and Legal
  • Head, Eye, Ear, Nose, and Throat
  • Hematology and Oncology
  • Human Behavior
  • Infectious Disease
  • Neurology
  • Obstetrics and Gynecology
  • Orthopedics
  • Pediatrics
  • Procedures and Skills
  • Psychiatry/Behavioral Health
  • Renal and Genitourinary
  • Resuscitation
  • Team Performance
  • Thoracic and Respiratory
  • Toxicology
  • Trauma

COVID-19: Remdesivir RCT #3 (5d vs 10d)

Background: We have covered the two previous RCTs on remdesivir on REBEL EM (RCT #1 and RCT #2). In the first trial by Wang et al , there was no statically significant improvement in clinical outcomes, but, there were trends ...

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Infectious Disease

The FISH RCT: Surgical vs Non-Surgical Management of Displaced Humeral Shaft Fractures

Background: Humeral shaft fractures are commonly seen in the Emergency Department and emergency management is relatively straightforward: assess for other trauma, assess for radial nerve injury, analgesia, sling or functional bracing and follow up with orthopedics. However, there are debates ...

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Orthopedics

REBEL Cast Ep83 – COVID-19 in the ICU, ECMO Early, & Steroids with Jeff Dellavolpe, MD

I am fortunate to work in a hospital system that is very forward thinking.  We have a phenomenal relationship with our intensivists, and I have been fortunate enough to have several discussions with them about how we are managing COVID-19 ...

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Infectious DiseaseResuscitationThoracic and Respiratory

COVID-19: IMV and Mortality at Emory

Background: One of the hot topics in COVID-19 care is the mortality rate associated with invasive mechanical ventilation (IMV). There have been early reports of IMV having mortality rates ranging from 50 to 90%.  These high rates are concerning but, ...

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Infectious DiseaseThoracic and Respiratory

New Opioid Use After Invasive Mechanical Ventilation and Hospital Discharge

Background Information: Physicians have and continue to heavily contribute to the current opioid epidemic in the United States and Canada.1 Although much of the focus has been opioid prescriptions given to patients in the emergency department,2,3 not much attention has ...

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Psychiatry/Behavioral HealthToxicology

REBEL Core Cast 34.0 – Chest Tubes

Take Home Points Small to Moderate Size Pneumothorax – consider managing conservatively with observation (need to make sure consulting services on same page) Needle aspiration for spontaneous pneumothorax recommend by British Thoracic and European Respiratory Societies 1 in 5 patients ...

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Procedures and Skills

Remdesivir ACTT-1: Adaptive COVID-19 Treatment Trial Part 1

Background: The saga of Remdesivir for treatment of COVID-19 continues. We previously covered two studies of this drug on REBEL EM (Link is HERE & Link is HERE). One trial (≈200pts) showed no difference in the primary outcome of median ...

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Infectious Disease

Rebellion in EM 2019: Got Milk? via Jenny Beck-Esmay, MD

“You’re working a shift in whatever the lower acuity version is of your department. So maybe it’s fast track, maybe you call it an urgent care. Whatever it is, it’s a unit where they take doctors, who trained for 7 ...

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Obstetrics and Gynecology

COVID-19 Update: Just Say No to Hydroxychloroquine or Chloroquine With or Without Macrolides

This publication has now been retracted by Lancet (June 4, 2020) Background: There is no conclusive evidence that chloroquine, or its derivative hydroxychloroquine, with or without a second-generation macrolide is effective in COVID-19 treatment or prophylaxis. Laboratory studies have shown ...

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Infectious Disease

COVID-19 vs H1N1: Similar but Different

Disclaimer: This post explores some of the pathophysiologic findings in severe SARS-CoV-2 infection. It explores possible mechanisms-based and posits theories BUT, this is not a clinical post. The hypothesis and findings here are not confirmed and extrapolation to management is ...

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Infectious Disease
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