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All Categories
  • All Categories
  • Abdominal and Gastrointestinal
  • Allergy and Immunology
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  • Endocrine, Metabolic, Fluid, and Electrolytes
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MR CLEAN-NO IV: Endovascular Treatment for Stroke Compared to Alteplase Followed by Endovascular Treatment: No Difference, But Also Not Not Worse

Background: While the effects of stroke can be both debilitating and devastating, the benefit of certain treatments have not always been clear and the data supporting them are fraught with controversy. Reanalysis of the two trials demonstrating the benefit of thrombolytics ...

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Neurology

REBEL Cast Ep106: The COCA Trial – Calcium in Cardiac Arrest

Background: The utility of pharmacological interventions for patients with OHCA are rather limited with no robust evidence that they improve outcomes.  Calcium, one of the pharmacological options has both inotropic and vasopressor effects. Additionally, calcium plays an important role in ...

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Resuscitation

REBEL Cast Ep 105: Thrombolysis Before Endovascular Therapy for LVO Acute Ischemic Stroke

In this episode of REBEL Cast, Anand Swaminathan and I sit down to discuss the utility of thrombolysis prior to Endovascular therapy for LVO acute ischemic stroke.  The discussion is broken up into two potential scenarios: Not all facilities are ...

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Neurology

COV-BARRIER Addendum Study: Baricitinib in ECMO/Mechanically Ventilated Patients with COVID-19

Background:  Despite access to vaccines in developed countries, COVID19 remains a nimble and persistent foe. While case counts wax and wane the virus continues to spread and mutate. The rapid development of vaccines has been helpful but the distribution across ...

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Infectious DiseaseThoracic and Respiratory

REBEL Core Cast 71.0 – Troubleshooting the Vent

Take Home Points: DOPES is not just a memory tool. It give you a structured approach to taking care of vented patients with vital sign changes. Check for dislodgement of the tube, obstruction of the tube, pneumothorax, equipment failure, breath ...

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Resuscitation

The HEP-COVID Trial: Therapeutic Anticoagulation in Non-Critically Ill COVID-19 Patients

Background: Patients with COVID-19 are at increased risk from thromboembolic phenomena. Patient-specific factors such as comorbidities and immobility have been linked to thrombosis. Disease-specific factors such as virus-induced endothelial changes and cytokine storm may also be triggers. Furthermore, patients with elevated ...

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Hematology and OncologyInfectious DiseaseThoracic and Respiratory

Meta-Analysis on Topical TXA for Epistaxis

Background Information: Epistaxis management in the emergency department has historically included topical vasoconstrictors, local anesthetics such as oxymetazoline and phenylephrine and topical fibrinolytic agents such as Tranexamic Acid (TXA). When these topical agents fail, packing, chemical cauterization or surgical ligation ...

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Head, Eye, Ear, Nose, and ThroatProcedures and SkillsResuscitation

Posterior Occlusion Myocardial Infarctions and STDmaxV1-4

Background: Not all occlusion myocardial infarctions (OMIs) present with classic ST-segment elevation (We have covered this on REBEL EM Before HERE, HERE, and HERE). OMIs of the “posterior” and “lateral” walls are the most commonly missed, with >50% of left ...

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Cardiovascular

REBEL Core Cast 70.0 – Open Fractures

Take Home Points: Prioritize ABCs and systematic evaluation of the trauma patient with an open fracture as one third of these patients have multiple injuries Assess neurovascular status and immediately reduce and immobilize if compromised Give appropriate antibiotics as soon ...

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OrthopedicsTrauma

The CAP-IT Trial: Amoxicillin Dose and Duration in Children with Community-Acquired Pneumonia

Background/Introduction: The commonly cited duration of antibiotic therapy (7-14 days) for community-acquired pneumonia (CAP) has historically been based on arbitrary timelines extrapolated from a desire to prevent treatment failures and avoid under-treatment rather than evidence-based medicine. Even the original literature on ...

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Infectious DiseasePediatrics
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