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Rebel Category: REBEL EM

Is 7 Days Enough? Rethinking Antibiotic Duration in Sepsis — The BALANCE Trial

Current IDSA guidelines for sepsis recommend individualized durations of antibiotic therapy based on source control and clinical response, but definitive guidance remains limited. Three small noninferiority RCTs suggested that 7 days of antibiotics may be sufficient for patients with gram-negative ...

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Infectious Disease

TNK vs tPA — The ORIGINAL Trial

The American Heart Association and the European Stroke Organization have updated their guidelines to recommend TNK as an alternative to tPA in patients eligible for thrombolysis. TNK, a bioengineered variant of tPA, has some advantages, including its single-dose administration, fibrin ...

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Neurology

Size Matters: The Impact of Cuff Size on Blood Pressure

Background: Accurate blood pressure (BP) measurement is essential in the emergency department (ED), where it serves as a key marker of hemodynamic stability and informs critical management decisions. Improper technique and incorrect cuff sizing can lead to falsely high or ...

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Procedures and Skills

Street Medicine: Compassionate Care for the Unhoused

Introduction: In this episode of Rebel Cast, host Marco Propersi, along with co-hosts Steve Hochman and Kim Baldino, delve into the practice and importance of street medicine—the direct delivery of healthcare to homeless and unsheltered individuals. Special guests Dr. Jim ...

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Is the D-Dimer Useful in High-Probabilty Pulmonary Embolism?

Bottom Line Up Top: A negative D-Dimer likely excludes significant pulmonary embolism (PE) in all patients but the low chance of getting a negative result makes a D-Dimer first approach of low clinical utility in the high pre-test probability ...

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Cardiovascular

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