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Rebel Category: REBEL EM

Minimalist comparison graphic of HAT vs SEDAN for estimating hemorrhage risk after stroke thrombolysis, featuring a grayscale brain, red lightning bolt, and labeled comparison circles.

MDCalc Wars: HAT vs SEDAN — Hemorrhage Risk After Stroke Thrombolysis

The HAT and SEDAN scores help estimate symptomatic intracranial hemorrhage risk after stroke thrombolysis. This comparison reviews what each tool measures, when to use them, and the key limitations clinicians should know.

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Neurology
Queen of Hearts playing card on a grayscale deck representing AI vs physicians in STEMI-equivalent and STEMI-mimic ECG interpretation

The Queen of Hearts Returns: AI vs Physicians in STEMI-Equivalent and STEMI-Mimic ECGs

STEMI-equivalent and STEMI-mimic ECGs are among the most difficult tracings to interpret. This study examines how Queen of Hearts AI performed against physicians when accuracy in cath lab activation decisions mattered most.

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Cardiovascular

Clinical Conundrum: Is Acetaminophen Safe in Pregnancy?

In the first trimester, fever is associated with increased risk of birth defects such as cleft lip and palate, as well as serious neural-tube defects such as spina bifida and anencephaly. In late pregnancy, fevers can boost the risk of ...

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Obstetrics and Gynecology

Diastology: Use E/e’ to Estimate Left Atrial Pressure

POCUS diastology doesn’t diagnose chronic diastolic dysfunction—it estimates left atrial pressure in real time. Learn how to capture E and e’ from an apical 4-chamber view, calculate E/e’, and rapidly distinguish cardiogenic pulmonary edema from other causes of acute dyspnea ...

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Procedures and SkillsResuscitation

The PEERLESS Trial: Large-Bore Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis in Intermediate-Risk PE

The optimal treatment strategy for intermediate-risk (submassive) pulmonary embolism remains controversial. These patients are not in shock, but they have right ventricular (RV) dysfunction and myocardial injury, which are associated with higher risk for clinical decompensation and adverse outcomes.

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Thoracic and Respiratory

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