Rebel Category: REBEL EM

CRYOSTAT-2: Early Empiric Cryoprecipitate in Major Trauma

Background: Hemorrhage is the leading cause of trauma related mortality. The initial injury is often complicated by multifactorial coagulopathy that can exacerbate bleeding.  Fibrinogen is the precursor to fibrin and a major component of stable clot formation. Fibrinogen and fibrin …

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Hematology and OncologyTrauma

Pediatric UTIs: Short-Course vs. Standard-Course Antibiotics — Is It Time for a Change?

Background: There is a shifting paradigm towards shorter durations of antibiotics in pediatric infections. Conflicting international guidelines recommend treatment of urinary tract infection (UTI) with antibiotic courses ranging from just 3 days to 7–14 days.1–4 Antimicrobial resistance is a global …

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Infectious DiseasePediatrics

Rosh Review EM Scholar Monthly Question

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The SQuID Protocol: SQ Insulin in DKA?

Background: DKA is traditionally treated with fluid resuscitation, electrolyte replacement, and intravenous infusions of insulin. However, it is unclear if all degrees (mild, moderate, severe) of DKA require the same intensive treatment. Mild to moderate DKA represents a subgroup of …

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Endocrine, Metabolic, Fluid, and Electrolytes

STREAM-2: Half-Dose Tenecteplase vs Primary PCI in Older Patients with STEMI?

Background: Primary PCI is the recommended reperfusion strategy in patients with STEMI and should be initiated within 2 hours after first medical contact.  In non-PCI-capable hospitals this goal is not always achievable due to delays in transfer.  In these cases, …

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