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Rebel Category: REBEL EM
Hydroxycobalamin vs Methylene Blue for Vasoplegic Shock from Cardiopulmonary Bypass
Background Information: Vasoplegic shock is defined as hypotension with normal or increased cardiac output and can commonly occur in post-cardiac surgery patients having received cardiopulmonary bypass. This dysregulation of vasodilation is associated with a mortality of close to 25%. After …
CRYOSTAT-2: Early Empiric Cryoprecipitate in Major Trauma
Background: Hemorrhage is the leading cause of trauma related mortality. The initial injury is often complicated by multifactorial coagulopathy that can exacerbate bleeding. Fibrinogen is the precursor to fibrin and a major component of stable clot formation. Fibrinogen and fibrin …
Pediatric UTIs: Short-Course vs. Standard-Course Antibiotics — Is It Time for a Change?
Background: There is a shifting paradigm towards shorter durations of antibiotics in pediatric infections. Conflicting international guidelines recommend treatment of urinary tract infection (UTI) with antibiotic courses ranging from just 3 days to 7–14 days.1–4 Antimicrobial resistance is a global …