Archive

Rebel Category: REBEL EM

The PEERLESS Trial: Large-Bore Mechanical Thrombectomy Versus Catheter-Directed Thrombolysis in Intermediate-Risk PE

The optimal treatment strategy for intermediate-risk (submassive) pulmonary embolism remains controversial. These patients are not in shock, but they have right ventricular (RV) dysfunction and myocardial injury, which are associated with higher risk for clinical decompensation and adverse outcomes.

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Thoracic and Respiratory
Minimal icon-style illustration of eyes, mouth, motor, respiration

MDCalc Wars: GCS Alternatives in the ED: SMS and FOUR Score

Need a quick, reliable coma scale in real ED chaos? SMS simplifies assessment, while FOUR adds brainstem and respiratory data when it matters most.

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NeurologyTrauma

Clinical Conundrum: Is Tamsulosin Effective in Increasing Spontaneous Passage Rate of Ureteral Stones?

Procalcitonin is a protein that is upregulated during inflammatory states. An elevation in procalcitonin should be specific to bacterial infections. Viral infections should result in decreased procalcitonin levels thus allowing us to differentiate bacterial from viral and help guide antibiotic ...

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Renal and Genitourinary

The Hope Trial: Alteplase 4.5–24 Hours After Stroke (CT Perfusion Selected)

The cornerstone of acute ischemic stroke (AIS) management involves timely reperfusion of the ischemic brain tissue. Intravenous thrombolysis with alteplase has been the standard of care for AIS within 4.5 hours of symptom onset, based on pivotal trials such as ...

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Neurology

REBEL Core Cast 150.0: Emergency Medicine Consults: How to Call a Consult + Handle Pushback (With Scripts)

Consults aren’t a formality—they’re a patient-care intervention. In this post, Swami breaks down how to call a consult in the ED using a simple 4-step framework (introduce yourself, lead with the ask, give a focused summary, and close the loop), ...

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