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Rebel Category: REBEL EM

Ottawa vs Pittsburgh Knee Rules title image comparing knee x-ray decision rules for acute knee injuries.

MDCalc Wars: Ottawa vs Pittsburgh — Which Knee Rule Should You Use?

Not every knee injury needs an x-ray. This post compares the Ottawa and Pittsburgh Knee Rules, highlighting when each rule applies, how they perform, and common pitfalls for ED clinicians.

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Orthopedics

Clinical Conundrum: What Is the Role of TXA in Dysfunctional Uterine Bleeding?

There are a number of accepted treatments for dysfunctional uterine bleeding (DUB) endometrial ablation and hysterectomy as well as medical treatments like hormonal therapy, NSAIDs and tranexamic acid (TXA). The American College of Obstetrics and Gynecology (ACOG) recommends the use ...

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Obstetrics and Gynecology

Systematic Review and Meta-Analysis of Preoxygenation Strategies For Intubation of Critically Ill Patients

What are the differences in efficacy and safety of HFNC, NIPPV, and facemask oxygen for preoxygenation of patients who are critically ill requiring tracheal intubation?

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ResuscitationThoracic and Respiratory
OPTION Trial tenecteplase for non-LVO stroke (late window, CT perfusion selected)

The OPTION Trial: Late-Window TNK for Non-LVO Stroke

The OPTION trial evaluated IV tenecteplase (0.25 mg/kg) in CT perfusion–selected non-LVO ischemic stroke patients treated 4.5–24 hours after last-known-well. Tenecteplase improved excellent 90-day outcomes (mRS 0–1) but increased symptomatic intracranial hemorrhage, with the benefit–harm balance sensitive to outcome and ...

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Neurology

The EVERDAC Trial: Non-Invasive BP vs Arterial Lines in the Critically Ill

The EVERDAC trial sought to determine if managing shock with noninvasive brachial cuff monitoring is noninferior to early (<4 hours) arterial catheter placement

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CardiovascularResuscitation
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