3 Apr 2019
April 3, 2019
Take Home Points on Non-Inferiority Studies
- Non-inferiority studies should be done when a new treatment (or diagnostic modality) requires less resources (cost or time), is easier for the patient or has a lower side-effect profile.
- Non-inferiority study design largely negates the protections against bias added by blinding and randomization.
- Non-inferiority studies can be used to manipulate clinicians when a superiority study would be more appropriate.