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The PREOXI Trial: Pre-Oxygenation with NIV vs Facemask

Background: Tracheal intubation is frequently performed in critically ill patients.  Hypoxemia is one of the major adverse events that can occur during intubation and it increases the risk of morbidity and mortality. Preoxygenation before induction of anesthesia increases the amount ...

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ResuscitationThoracic and Respiratory

Should End-Tidal Capnometry (ETC) During ED Procedural Sedation/Analgesia (PSA) Not Be Standard Care?

Background: Procedural sedation and analgesia (PSA) is a frequently employed in the emergency department (ED) to facilitate painful procedures. Some of the potential untoward effects of PSA include cardio-respiratory depression and/or airway compromise.  Standard practice in many parts of the ...

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Procedures and Skills

REBEL Core Cast 125.0 – Hyperkalemia

Take Home Points Always obtain an EKG in patients with ESRD upon presentation Always obtain an EKG in patients with hyperkalemia as pseudohyperkalemia is the number one cause If the patient with hyperkalemia is unstable or has significant EKG changes ...

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Endocrine, Metabolic, Fluid, and Electrolytes

Sympathetic Crashing Acute Pulmonary Edema: High-Dose Vs. Low-Dose Nitro

Background: Sympathetic Crashing Acute Pulmonary Edema (SCAPE) results from an increased systemic vascular resistance and activation of the Renin-Angiotensin-Aldosterone System (RAAS), which causes increased sodium/water reabsorption and worsening cardiac function. Additionally, sympathetic activation shifts fluid from splanchnic beds into the ...

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ResuscitationThoracic and Respiratory

REBEL Core Cast 124.0 – Hyperinsulinemia Euglycemia Therapy

Take Home Points Management of severe beta-blocker and calcium-channel blocker toxicity should occur in a stepwise fashion: potential gastric decontamination, multiple lines of access, judicious fluids, calcium, glucagon, and vasopressors as needed. Initiation of high dose insulin therapy requires a ...

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Toxicology

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