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Rebel Category: REBEL EM

It’s Raining Steroids in COVID-19: REMAP-CAP, CoDEX, & CAPE COVID

Background: Over the past few years, corticosteroids have gained traction in the treatment of patients with ARDS and septic shock.  Trials such as APROCCHSS and ADRENAL have shown that the use of corticosteroids is associated with more rapid resolution of ...

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Infectious Disease

The THALES Trial: Ticagrelor and Aspirin vs Aspirin Alone in Acute Ischemic Stroke or TIA

Background: The risk of a subsequent ischemic stroke in the first few months after an acute ischemic stroke or transient ischemic attack is approximately 5 to 10%. In these patients Aspirin has been used to prevent secondary ischemia, and trials ...

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Neurology

Multisystem Inflammatory Syndrome in Children (MIS-C) vs Kawasaki Disease

Case Presentation: A 4-year-old previously healthy Hispanic female presented to the ED with a diffuse rash and facial swelling, concerning for an apparent allergic reaction. She was rushed into the treatment area for evaluation of possible anaphylaxis and respiratory assessment. ...

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Infectious DiseasePediatrics

Infectious Acute Transverse Myelitis Secondary to COVID-19

The Coronaviridae family and its genera coronaviruses have been implicated as having neurotropic and neuroinvasive capabilities in human hosts (Bohmwald 2018). They have been associated with the development of neuropsychiatric symptoms, seizure activity, encephalomyelitis, acute flaccid paralysis, cerebral venous sinus ...

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Infectious DiseaseNeurology

GRECCO-19: Colchicine for COVID-19?

Background: The most severe SARS-CoV-2 infections result in an intense inflammatory response which can lead to acute lung injury and/or acute respiratory distress syndrome.  Theoretically, potential treatments for severe disease should have anti-inflammatory action without substantial side effects. One candidate ...

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Infectious Disease

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