Archive

Rebel Category: REBEL Crit

Anaphylactic Shock

Anaphylactic Shock is an acute, life-threatening hypersensitivity disorder, with a generalized, rapidly evolving, multi-systemic allergic reaction (IgE-mediated disorder). If not treated rapidly can become fatal. Scott Weingart, MD put together  a manual titled the Resuscitation Crisis Manual, which in short, ...

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Allergy and ImmunologyResuscitation

The Safety and Efficacy of Push Dose Vasopressors in Critically Ill Adults

Background Information: Acute Hypotension is associated with increased morbidity and mortality. Continuous vasopressor infusions have previously been the mainstay of treatment. However, peripherally dosed push dose pressors, (PDPs), are beginning to be administered more frequently for management of acute hypotension.1-4 ...

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CardiovascularResuscitation

The CT FIRST Trial: Should We Pan-CT After ROSC?

Background: Achieving ROSC in out of hospital cardiac arrest (OHCA) is no easy feat but, care doesn’t end with ROSC. Post-ROSC management is nuanced and challenging but helps to ensure good outcomes. Identification of the underlying cause of the cardiac ...

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CardiovascularResuscitation

Adjunctive Methylene Blue in Septic Shock?

Background: Sepsis can induce numerous physiologic derangements.  At the most severe end, this includes endothelial dysfunction leading to increased vascular permeability, abnormal nitric oxide metabolism, and vasodilation (i.e. septic shock).  Judicious fluid resuscitation is indicated in patients with signs of ...

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Infectious DiseaseResuscitation

REBEL Cast Ep116: The CLOVERS Trial – Restrictive vs Liberal Fluids in Sepsis-Induced Hypotension

Background: IV fluids are part of the standard resuscitation bundle in septic shock, however it is unclear if they provide a significant benefit. These patients can have a vasodilated vascular bed and the initial use of fluids is hypothesized to ...

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Infectious DiseaseResuscitation

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