January 29, 2020
Take Home Points
- When compared to 0.9% saline, lactated ringers is a more balanced solution and more closely resembles our serum.
- SALT ED and SMART trials show normal saline may increase the occurrence of major adverse kidney events in comparison to a balanced solution like LR. For large volume resuscitations, LR is a better choice.
- Certain medications cannot be run with LR in the same IV line. Ampicillin, Carbapenems, Phenytoin, Potassium Phosphate, Nicardipine
- Ceftriaxone and LR should never be running at the same time in children less than 28 days old.