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Medical Category: Infectious Disease

Pearls from ResusX Rewired 2020

From Oct 6th – 8th, 2020, Haney Mallemat (@CriticalCareNow) and his team put on an absolutely amazing online critical care conference called ResusX Rewired.  ResusX is a conference designed by resuscitationists to provide clinicians with the most up to date ...

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CardiovascularEndocrine, Metabolic, Fluid, and ElectrolytesInfectious DiseaseProcedures and SkillsResuscitationThoracic and RespiratoryToxicologyTrauma

US Expanded Access Program: Convalescent Plasma, Mortality, and COVID-19

Background: Convalescent plasma therapy (CPT) is not a novel treatment modality.  It has been used in other illnesses such as SARS, MERS, and Ebola with variable results. The theory behind CPT is to take antibody rich blood from patients who ...

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Infectious Disease

The ALIC4E Trial: Oseltamivir + Usual Care vs Usual Care Alone

Background: Previous evidence has found that oseltamivir reduces median time to alleviation of influenza symptoms over placebo by about 1 day.  The benefits were greater when treatment was initiated within 24 to 48 hours of symptoms onset. Many previous trials ...

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Infectious Disease

REBEL Cast Ep86: Baloxavir for Influenza Prophylaxis

Background: Baloxavir (trade name Xofluza) was approved for the treatment of acute, uncomplicated influenza in patients > 12 years of age in October 2018. However, high-quality data has been underwhelming at best for its efficacy in treatment. Back in November ...

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Infectious Disease

Let’s Get Our ACTS Together: The Metabolic Cocktail and Septic Shock Again

Background: Though it’s been stated numerous times on this blog, it bears repeating: the pillars of sepsis care remain early identification of sepsis, early appropriate empiric antibiotics, source control, and supportive care. The focus should be on getting the basics ...

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Infectious Disease

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