Archive

Tag: Pulmonary Embolism

sPESI vs Bova Score title image showing pulmonary embolism risk stratification with discharge and monitoring icons.

MDCalc Wars: sPESI vs Bova Score — PE Risk Stratification Made Practical

Not every normotensive PE patient is truly low risk. sPESI helps identify patients who may be safe for outpatient management, while Bova helps recognize patients at risk for early deterioration despite initially stable vital signs.

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Hematology and OncologyThoracic and Respiratory

HI-PEITHO Trial: Ultrasound-facilitated, Catheter Directed Fibrinolysis for PE

In patients with intermediate-risk pulmonary embolism (PE), does ultrasound-facilitated, catheter-directed fibrinolysis (US-CDT) plus anticoagulation improve clinical outcomes compared to anticoagulation alone?

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ResuscitationThoracic and Respiratory

MDCalc Wars: Stop Before the CT! — Are You Using PERC or Wells Correctly

Diagnosing PE in the emergency department is tricky. The symptoms—chest pain, shortness of breath, tachycardia—are nonspecific and overlap with many other conditions. But missing a PE can have devastating consequences, so there’s often a low threshold to order a CTA. ...

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Thoracic and Respiratory

REBEL Cast Ep125: 1st 48 Hours of PE Management – How Good Is Unfractionated Heparin?

Background: The mainstay of treatment for symptomatic pulmonary embolism  (PE) is anticoagulation (AC).  Patients with higher-risk PE may require advanced interventions such as thrombolytic therapy, surgical thrombectomy, or even extracorporeal membrane oxygenation (ECMO). Because of its short half-life and availability ...

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CardiovascularHematology and OncologyResuscitationThoracic and Respiratory

REBEL Cast Ep123: Reduced-Dose Systemic Peripheral Alteplase in Massive PE?

Background: Massive pulmonary embolism  defined as sustained hypotension (SBP <90mmHg)  has a high mortality which is why early recognition and thrombolytic therapy is typically recommended (AHA Class IIA; ESC Class IB) . However, full-dose thrombolytic therapy (Alteplase 100mg (IV) is  associated ...

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CardiovascularResuscitationThoracic and Respiratory
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