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Tag: Pulmonary Embolism

The PEAPETT Trial: Half Dose tPA for PEA due to Massive Pulmonary Embolism

Background: Anyone who has run a code, knows that pulseless electrical activity (PEA) during cardiac arrest has a worse prognosis compared to patients with shockable rhythms.  In patients with suspected massive PE as the cause of their cardiac arrest the …

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Resuscitation

Should I Stay or Should I Go: Outpatient Treatment of Venous Thromboembolism

Background: The care of venous thromboembolism (VTE) is currently undergoing a paradigm shift in the US with an increasingly large percentage of patients being discharged home from the Emergency Department (ED).  It wasn’t too long ago that all patients diagnosed …

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Hematology and Oncology

Treatment of Submassive Pulmonary Embolism (PE): Full Dose, Half Dose, or No Dose?

Submassive pulmonary embolism (PE) is responsible for approximately 20% of all PEs.  Although the in-hospital mortality has been reported as about 5%, there is significant morbidity associated with this diagnosis such as chronic pulmonary hypertension, impaired quality of life, persistent …

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Thoracic and Respiratory

REBEL Cast Episode 30: The PESIT Trial – Do All Patients with 1st Time Syncope Need a Pulmonary Embolism Workup?

Background: Syncope is a very frustrating chief complaint for many in the medical field.  There is no gold standard test and no validated decision instrument. It represents about 3 – 5% of ED visits, 1 – 6% of hospital admissions, …

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Thoracic and Respiratory

Catheter Directed Thrombolysis: The Magic Bullet for Submassive Pulmonary Embolism?

Background: When evaluating therapeutic options for PE, there are three categories in my mind: Subsegmental, Submassive, and Massive. For simplicity sake lets just say subsegmental PEs get treated with anticoagulation and massive PEs get treated with thrombolysis. The submassive category …

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Thoracic and Respiratory

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