Archive

Tag: Corticosteroids

REBEL Core Cast 149: Review of Corticosteroids in Community-Acquired Pneumonia

Corticosteroids have long sparked debate in the treatment of bacterial pneumonia — once viewed with skepticism, now increasingly supported by high-quality evidence. In this episode, Dr. Alex Chapa joins the REBEL Core Cast team to explore how the 2023 Cape ...

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Thoracic and Respiratory

Combination Inhalers in Asthma: Time to Switch?

🧭 REBEL Rundown 📌 Key Points 💨 Most asthma patients still leave the ED with a SABA alone—time for an upgrade. 📉 SABA/ICS combo inhalers cut severe exacerbations compared to SABA alone. 🏥 Study excluded typical ED patients—few had recent ...

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Thoracic and Respiratory

Corticosteroids in Severe Community Acquired Pneumonia: Could CAPE COD catalyze a change in critical care management?

Background: Community-acquired pneumonia (CAP) can lead to pulmonary and systemic inflammation, resulting in impaired gas exchange, sepsis, organ failure, and an increased risk of death. Corticosteroids have excellent anti-inflammatory and immunomodulatory effects that could mitigate some of the inflammation caused ...

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Dexamethasone vs Methylprednisolone in ICU Patients with COVID19

Background Information: Over one year into the pandemic many therapies to treat COVID-19 have targeted innumerable aspects of the virus. Most recently, the use of corticosteroids to treat the virus’ excessive inflammatory effects has become the front and center of ...

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Endocrine, Metabolic, Fluid, and ElectrolytesInfectious DiseaseThoracic and Respiratory

GLUCOCOVID: A Controlled Trial of Methylprednisolone in COVID-19 Pneumonia

Background Information: The use of corticosteroids in patients with pneumonia secondary to COVID-19 has been a controversially hot topic, particularly early on in the pandemic. Prior evidence seen in Severe Acute Respiratory Syndrome (SARS) and Middle Eastern Respiratory Syndrome have ...

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Infectious DiseaseThoracic and Respiratory

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