Archive

Author: Salim Rezaie

RAFF2: Electrical vs Pharmacological Cardioversion for ED Patients with Acute Atrial Fibrillation

Background: Acute atrial fibrillation (AF) is one of the most common dysrhythmias seen in the emergency department (ED). There has been extensive discussion and debate about the best way to manage acute AF centered around rate and rhythm control.  However, …

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Cardiovascular

COVID-19 Treatment Update: Can We Just Stop Wasting Time on Hydroxychloroquine

Background: Hydroxychloroquine (HCQ) is an antimalarial and immunomodulatory drug that is postulated to exert an antiviral effect by increasing intracellular pH resulting in decreased viral binding at the ACE2 receptor. Azithromycin is a macrolide antibiotic that also has anti-inflammatory and …

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Infectious Disease

ISAR-REACT 5 Trial: Ticagrelor vs Prasugrel in ACS

Background: In patients presenting to the ED with acute coronary syndrome (ACS), dual antiplatelet therapy is the current standard treatment.  This typically consists of aspirin and an adenosine diphosphate receptor antagonist.  It is fairly well understood that prasugrel and ticagrelor …

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Cardiovascular

REBEL Cast Ep85: The HALT-IT Trial – TXA in Acute GI Bleeds

Background: Acute gastrointestinal bleeding (GIB) is a common diagnosis dealt with by emergency clinicians.  Definitive therapy for acute GIB often includes endoscopy or surgery. However, there is a myriad of pharmaceutical options (i.e. PPI, Somatostatin Analogues, Antibiotics, etc.) as well …

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Abdominal and Gastroinstestinal

The RECOVERY Trial: Dexamethasone for COVID-19?

Background: We have been in need of a sign of hope in the fight against SARS-CoV-2 as it runs from city to city overwhelming health systems.  The majority of patients will be either asymptomatic or have only mild disease.  These …

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Infectious Disease

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