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Medical Category: Infectious Disease

ANDROMEDA-SHOCK: Peripheral Perfusion vs Serum Lactate in Septic Shock

Background: Based on the Surviving Sepsis Campaign, hemodynamic resuscitation of sepsis patients is done by repeating serum lactic acid levels every 2 – 4 hours until normalization. The issue with this strategy is that there are other things that may elevate ...

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Infectious Disease

The CENSER Trial: Early Norepinephrine in Septic Shock

Background: Standard management of septic shock has included, IV fluids until optimal intravascular volume is achieved, appropriate early antibiotics, and source control.  Typically, only after all these measures have been undertaken is vasopressor infusion initiated if a MAP of ≥65mmHg is ...

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Infectious Disease

Omadacycline, the NEJM and Non-Inferiority Studies

Introduction: The production and release of new antibiotics is rare and should be celebrated by clinicians. As antibiotic resistance continues to mount, our options narrow and, in turn, our patients suffer. Recently, the NEJM published two articles on a new ...

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Infectious Disease

IDSA Guideline on Seasonal Influenza Management 2018

Article: Uyeki TM et al. Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza. Clin Infect Dis 2018. PMID: 30566567 Background: Influenza is an Emergency Department ...

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Infectious Disease

REBEL Cast Ep 61: Diagnostic Questions in Urinary Tract Infections in the Elderly

Introduction: Beyond the Data The evolution from eminence-based to evidence-based care has come to define bedside emergency medicine, with rigorous skepticism and scholarly consideration accelerated by the power of global connectivity. Where anecdote and opinion once drove therapy, clinicians now ...

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Infectious Disease
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