Archive

Author: Rick Pescatore

Rimegepant and Inflammatory Neuropeptide Antagonism in Migraine

Background: Migraine is a chronic neurologic disease characterized by attacks of throbbing, often unilateral headache that are exacerbated by physical activity and associated with photophobia, phonophobia, nausea, vomiting, and, in many patients, cutaneous allodynia. Migraine is very common, and the burden …

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Neurology

REBELCast Ep63: LIDOKET – IV Lidocaine for Renal Colic?

Background: The use of intravenous lidocaine for analgesia in patients presenting to the emergency department (ED) with renal colic has gained recent traction and interest, and was previously explored on the REBEL EM blog. Literature has been mixed, with one …

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Renal and Genitourinary

REBEL Cast Ep 61: Diagnostic Questions in Urinary Tract Infections in the Elderly

Introduction: Beyond the Data The evolution from eminence-based to evidence-based care has come to define bedside emergency medicine, with rigorous skepticism and scholarly consideration accelerated by the power of global connectivity. Where anecdote and opinion once drove therapy, clinicians now …

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Infectious Disease

D-Dimer in Pregnancy: Limiting Radiation with Pre-test Probability

Background: Pulmonary embolism is the leading cause of death in pregnancy and the puerperium – accounting for nearly 20% of maternal deaths in the United States – making rapid and accurate diagnosis critically important for emergency physicians, OB/GYNs, and all …

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Hematology and OncologyObstetrics and Gynecology

Is Macrobid Safe in 1st Trimester Pregnancy?

Background: In 2011, the American College of Obstetricians and Gynecologists (ACOG) released a committee opinion warning against the use of nitrofurantoin (Macrobid) during the first trimester of pregnancy due to the perceived risk of an increased rate of congenital abnormalities …

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Obstetrics and Gynecology

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