Background: The Calcium for Out-of-Hospital Cardiac Arrest (COCA) trial was a randomized, placebo-controlled, double-blind trial of calcium compared to placebo in OHCA. COCA found no improvement in sustained ROSC but, rather, a trend towards harm for their primary outcome. Additionally, …
Background: Traumatic lacerations presenting to the emergency department are, by definition, contaminated (ie non-sterile). Standard management involves irrigation, local anesthesia, closure and tetanus update if required. The existing literature has never shown benefit to sterile gloves in these types of …
Background: Some of the feared complications of endotracheal intubation include hypotension, cardiac arrest, and death (cardiovascular collapse). These complications can result from numerous causes including medication-induced vasodilation and decreased venous return to the heart due to increased intrathoracic pressure from …
Background: The use of topical tranexamic acid (TXA) for anterior epistaxis has been studied in many trials with conflicting results. The largest and most methodologically rigorous study to date on the use of topical TXA in epistaxis has been the …
Background: Respiratory support is a common intervention in pediatric ICUs and can include HFNC and CPAP/BPAP to avoid invasive mechanical ventilation. HFNC has become more popular due to its ease of use, perceived patient comfort, and the ability to discharge …
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