Archive

Author: Salim Rezaie

The DANMASK-19 Trial: Masks Not Effective to Prevent COVID-19? Not So Fast!!!

Background: Face masks can reduce transmission of respiratory viruses by both being a potential physical barrier and by reducing droplet transmission.  Additionally, the presence of a mask reduces the users frequency of touching their face which may also reduce transmission.  ...

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Infectious Disease

A COVID-19 Update that is Long Overdue

Background: There have been lots of trials sitting on my computer desktop awaiting my review, but like many of you time has been thin from clinical work and increasing cases of COVID-19 where I work.  I thought it might be ...

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Infectious Disease

REBEL Cast Ep 89: The CODA Trial – Antibiotics vs Appendectomy for Appendicitis

Background: The well-established, standard treatment for acute appendicitis is surgical appendectomy.  However, recent research has challenged the dominance of the surgical approach in looking at antibiotics alone. The available literature on non-operative treatment of appendicitis (NOTA) has important limitations: exclusion ...

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Abdominal and GastroinstestinalInfectious Disease

REBEL Cast Ep88: The MIDAS Trial – Midodrine vs Placebo for Pressor Discontinuation

Background: ICU discharge is often delayed due to intravenous vasopressor requirements to maintain clinically indicated blood pressure goals. In some patients without impairment of tissue oxygenation, the use of oral agents could facilitate weaning from IV vasopressors and lead to ...

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Resuscitation

COVID-19: An EBM Take

The Novel Coronavirus 2019, was first reported on in Wuhan, China in late December 2019.  The outbreak was declared a public health emergency of international concern in January 2020 and on March 11th, 2020, the outbreak was declared a global ...

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Infectious Disease

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