Archive

Tag: TXA

TXA for Hemoptysis: We Put That $#!t on Everything (That Bleeds)

Hemoptysis is a potentially life-threatening emergency that can lead to airway compromise and hemorrhagic shock. While definitive treatments like bronchoscopy, bronchial artery embolization (BAE), and surgery can be effective, they often require significant time and specialized resources—capabilities not universally available ...

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ResuscitationThoracic and Respiratory

Rethinking the Role of TXA: Are We Asking Too Much?

Background: Injuries are a major cause of death worldwide. Hemorrhage accounts for about 1/3 of all trauma deaths and as such, it should be our goal to find treatments to decrease death from hemorrhage. Our bodies have a finely tuned ...

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Trauma

Topical TXA in Atraumatic Anterior Epistaxis Yet Again

Background: The use of topical tranexamic acid (TXA) for anterior epistaxis has been studied in many trials with conflicting results. The largest and most methodologically rigorous study to date on the use of topical TXA in epistaxis has been the ...

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Head, Eye, Ear, Nose, and Throat

Classic Journal Club: TXA for Epistaxis

Background: Epistaxis is a common ailment experienced by millions worldwide. While most of these cases can be managed by patients at home, some will require medical attention. Initial interventions include local pressure, ice, and forward head positioning for persistent bleeds. When ...

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Head, Eye, Ear, Nose, and ThroatHematology and Oncology

Meta-Analysis on Topical TXA for Epistaxis

Background Information: Epistaxis management in the emergency department has historically included topical vasoconstrictors, local anesthetics such as oxymetazoline and phenylephrine and topical fibrinolytic agents such as Tranexamic Acid (TXA). When these topical agents fail, packing, chemical cauterization or surgical ligation ...

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Head, Eye, Ear, Nose, and ThroatProcedures and SkillsResuscitation

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