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Tag: TXA

Topical TXA in Epistaxis

Background: Epistaxis is a common Emergency Department (ED) complaint with over 450,000 visits per year and a lifetime incidence of 60% (Gifford 2008, Pallin 2005). Standard anterior epistaxis treatment consists of holding pressure, use of local vasoconstrictors, topical application of silver …

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Head, Eye, Ear, Nose, and Throat

It’s Time for Tranexamic Acid (TXA) in Massive Hemorrhage

Background: Bleeding from massive hemorrhage in trauma and post-partum are a major cause of death worldwide. There have been two large randomized controlled trials, in trauma and post-partum hemorrhage that have shown administration of TXA within 3 hrs of bleeding …

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Trauma

The WOMAN Trial: Early TXA in Post-Partum Hemorrhage

Background: Post-partum hemorrhage (PPH) is the leading cause of maternal death worldwide. It is typically defined as > 500 ml of blood loss within 24 hours of giving birth. However, PPH encompasses a broad spectrum of disease from mild oozing …

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Obstetrics and Gynecology

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