Archive

Tag: OHCA

COCA Trial Follow-Up: Calcium vs Placebo on Long-Term Outcomes of OHCA

Background: The Calcium for Out-of-Hospital Cardiac Arrest (COCA) trial was a randomized, placebo-controlled, double-blind trial of calcium compared to placebo in OHCA.  COCA found no improvement in sustained ROSC but, rather, a trend towards harm for their primary outcome. Additionally, ...

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CardiovascularResuscitation

External Validation of Pittsburgh Cardiac Arrest Category (PCAC) Illness Severity Score

Background Information: Multiple illness severity scores have been developed for use after out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). Unfortunately, these rely on information that is not immediately available to providers in the early hours following return of ...

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CardiovascularNeurologyResuscitation

Effect of Intra-Arrest Transport and eCPR on Neurologic Outcomes in Refractory OHCA

Background Information: Refractory out of hospital cardiac arrest (OHCA) is defined as prolonged cardiac arrest and cardiac arrest without return of spontaneous circulation (ROSC). In addition to an already morbid condition, the chances of these patients surviving drops below 5% ...

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CardiovascularNeurologyResuscitation

REBEL Cast Ep106: The COCA Trial – Calcium in Cardiac Arrest

Background: The utility of pharmacological interventions for patients with OHCA are rather limited with no robust evidence that they improve outcomes.  Calcium, one of the pharmacological options has both inotropic and vasopressor effects. Additionally, calcium plays an important role in ...

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Resuscitation

REBEL Cast Ep101: The TOMAHAWK Trial – Angiography after OHCA without STEMI

Background: The clinical importance of immediate coronary angiography after out of hospital cardiac arrest (OHCA) without STEMI continues to be debated. A systematic review and meta-analysis published in 2016 suggested that this set of patients has a high likelihood of ...

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CardiovascularResuscitation
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