Archive

Medical Category: Trauma

REBEL Cast Ep109: The RePHILL Trial

Background: Currently, trauma resuscitation focuses on immediate hemorrhage control, resuscitation with blood products (i.e. PRBCs, plasma) and early administration of tranexamic acid.  The evidence for the use of blood-based resuscitation in the pre-hospital system has been mixed (PAMPer and COMBAT …

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Hematology and OncologyTrauma

REBEL Core Cast 80.0 – Compartment Syndrome

Take Home Points Compartment syndrome is a life and limb threatening emergency that requires early recognition, prompt diagnosis and immediate management with fasciotomy While clinical evaluation is flawed, pain out of proportion to injury and pain with passive stretch of …

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Trauma

Andexanet Alfa Vs. Four-Factor PCC: Is Andexanet Alfa Worth The Hype?

Background: Oral factor Xa inhibitors (FXi) have been associated with major and fatal bleeding events, including intracranial hemorrhage (ICH). In randomized controlled trials, both rivaroxaban and apixaban are associated with ICH at rates that range from 0.1 to 4% (Agnelli …

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Hematology and OncologyNeurologyTrauma

PECARN Blunt Abdominal Trauma: Is A Clinical Decision Instrument Better Than Clinician Gestalt?

Background: Unintentional injuries remain the leading cause of mortality in children. While traumatic brain injuries and thoracic traumas are the top two causes of mortality and morbidity, abdominal traumas are the third most common cause.  Additionally, children are at higher …

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PediatricsTrauma

REBEL Core Cast 70.0 – Open Fractures

Take Home Points: Prioritize ABCs and systematic evaluation of the trauma patient with an open fracture as one third of these patients have multiple injuries Assess neurovascular status and immediately reduce and immobilize if compromised Give appropriate antibiotics as soon …

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OrthopedicsTrauma

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