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All Categories
  • All Categories
  • Abdominal and Gastrointestinal
  • Allergy and Immunology
  • Cardiovascular
  • Dermatology
  • EMS and Disaster
  • Endocrine, Metabolic, Fluid, and Electrolytes
  • Environmental
  • Ethical and Legal
  • Head, Eye, Ear, Nose, and Throat
  • Hematology and Oncology
  • Human Behavior
  • Infectious Disease
  • Neurology
  • Obstetrics and Gynecology
  • Orthopedics
  • Pediatrics
  • Procedures and Skills
  • Psychiatry/Behavioral Health
  • Renal and Genitourinary
  • Resuscitation
  • Team Performance
  • Thoracic and Respiratory
  • Toxicology
  • Trauma

Delirium in Critical Illness: Haloperidol vs Ziprasidone?

Background Information: Delirium is defined as an acute disorder of consciousness which can occur in up to 80% of mechanically ventilated ICU patients.1-5 This acute cognitive dysfunction is associated with prolonged hospital stay, increased mortality, longer periods of mechanical ventilation and long-term ...

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Psychiatry/Behavioral Health

Baloxavir (Xofluza), a New Influenza Anti-Viral Medication is FDA Approved, But Does it Work?

Background: On October 24th, 2018, Roche, the maker of oseltamivir, announced that the US Food and Drug Administration (FDA) approved Xofluza (baloxavir marboxil) for the treatment of acute, uncomplicated influenza in people 12 years of age and older. Historically, there ...

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Infectious Disease

Cricoid Pressure in Airway Management: The IRIS Trial

Background: Cricoid pressure is dead, right? Many have made this claim including a brilliant argument against its use by John Hinds here. Despite the many eulogies, we continue to hear about cricoid pressure so it makes sense that we dive ...

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Procedures and Skills

Today I Learned: A Daily Dose of #FOAMed 1.0

In October 2016, I was exposed to the vast world of Free Open Access Medical Education and MedTwitter. I was astounded and inspired by the different educators who were trying to make learning easier. The Knowledge Translation (KT) gap was ...

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Dual Sequential Defibrillation (DSD)

Background: In the United States 424,000 out of hospital cardiac arrests occur per year with a 10.4% overall survival rate.1 Refractory Ventricular Fibrillation (RVF) is a complication of cardiac arrest and has varying definitions in the literature but is commonly defined ...

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Resuscitation

REBEL Cast Ep60: COMBAT and PAMPer – Prehospital Plasma in Trauma

Background: Care of trauma patients with severe bleeding has advanced in recent years with a focus on damage control resuscitation which includes permissive hypotension, hemostatic resuscitation (blood component resuscitation), and hemorrhage control. Minimizing crystalloids in favor of blood component-based resuscitation in ...

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Trauma

Information Overload: Drinking from the Firehose

Background: Keeping up to date with the current literature is no small task.  You may say it is like drinking from a firehose when you’re thirsty;  it can be painful and, at the end, does it really quench our thirst?  The ...

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The ORBITA Trial: PCI vs Placebo Procedure for Angina Relief in Stable Angina

Background:In the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial , there was no difference in MI and death rates between patients with stable coronary artery disease who underwent PCI and controls. In stable angina, the primary goal of ...

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Cardiovascular

Performing Procedures Like a Boss, in the ED Without an IV

Background: Establishing IV access has become the norm for patients presenting to the ED.  However with increasing patient volumes, difficulty and delays in acquiring IV access, it seems that anything that could expedite care, reduce pain and suffering, and improve patient ...

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Procedures and Skills

The Tamiflu Debacle

Background:  Oseltamivir (Tamiflu), a neuraminidase inhibitor, was approved by the FDA in 1999.  The majority of the evidence supporting the use of the medication came from trials funded by Roche, the maker of the drug. Safety issues with the drug ...

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Infectious Disease
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