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Alternative Headache Therapies

Background: Presentations to the Emergency Department for acute headache are remarkably common, with more than 2 million visits each year in the United States (Goldstein 2006). Emergency clinicians are tasked with dual roles of excluding life-threatening pathology while rendering effective pain ...

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Neurology

Is Amiodarone Dead?

Background: Amiodarone is a class III antidysrhythmic first released for human use in 1962. As with other drugs in this class, amiodarone acts by blocking potassium channels thus prolonging the action potential. This, in turn, leads to a lengthening of depolarization ...

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CardiovascularResuscitation

Initial Antibiotic Choice in Uncomplicated Cellulitis

Background: Cellulitis is a common emergency department (ED) presentation. Despite the fact that diagnosis remains relatively straight forward, complexity remains in management in terms of the causative agent and appropriate antibiotic regimen. Though beta-hemolytic Streptococci are the most common causative ...

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Infectious Disease

Should You Give Albumin in Spontaneous Bacterial Peritonitis (SBP)?

The Background: Nearly 50% of patients in the U.S. with cirrhotic liver disease develop ascites over a 10-year period of observation, placing them at risk for developing spontaneous bacterial peritonitis (SBP) (Runyon 2012). It is estimated that 12-25% of patients with ...

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Infectious Disease

What's Your Drug Shortage Plan: Part II

Many drugs critical to patient management are showing up on national shortages (most pertinent to the ED list below).  Is your institution feeling the effects?  Do you have a drug shortage plan? In this post we will cover potential alternatives ...

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What’s Your Drug Shortage Plan: Part II

Many drugs critical to patient management are showing up on national shortages (most pertinent to the ED list below).  Is your institution feeling the effects?  Do you have a drug shortage plan? In this post we will cover potential alternatives ...

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What's Your Drug Shortage Plan: Part I

Many drugs critical to patient management are showing up on national shortages (most pertinent to the ED list below).  Is your institution feeling the effects?  Do you have a drug shortage plan? In this post we will cover potential alternatives ...

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What’s Your Drug Shortage Plan: Part I

Many drugs critical to patient management are showing up on national shortages (most pertinent to the ED list below).  Is your institution feeling the effects?  Do you have a drug shortage plan? In this post we will cover potential alternatives ...

Read More

Acute Salicylate Toxicity, Mechanical Ventilation, and Hemodialysis

Background: Salicylates are common substances that can be purchased over the counter. They are readily available, and in the setting of an overdose, can be fatal . Initially, as salicylates are metabolized, they can induce a respiratory alklalosis. This is ...

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Toxicology

The WOMAN Trial: Early TXA in Post-Partum Hemorrhage

Background: Post-partum hemorrhage (PPH) is the leading cause of maternal death worldwide. It is typically defined as > 500 ml of blood loss within 24 hours of giving birth. However, PPH encompasses a broad spectrum of disease from mild oozing ...

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Obstetrics and Gynecology
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