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Author: Marco Propersi

The MOVe-Out Trial: Molnupiravir – Oral Antivirals for Management of Covid-19?

Background: On December 23, 2021, the FDA granted molnupiravir emergency use authorization for the treatment of patients with Covid-19. Molnupiravir is a nucleoside analog that inhibits SARS-CoV-2 replication and triggers viral RNA mutagenesis. Until the release of oral antivirals, clinicians …

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The Pragmatic Combination of YEARS Score and Age-Adjusted D-Dimer

Background: The optimal approach to risk stratifying patients for pulmonary embolism (PE) remains elusive. Multiple decision instruments are available with varying degrees of complexity and acceptance among emergency medicine clinicians (Wells, Geneva, PERC, YEARS, age-adjusted D-dimer). The 2018 ACEP clinical …

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CardiovascularHematology and OncologyThoracic and Respiratory

The HEP-COVID Trial: Therapeutic Anticoagulation in Non-Critically Ill COVID-19 Patients

Background: Patients with COVID-19 are at increased risk from thromboembolic phenomena. Patient-specific factors such as comorbidities and immobility have been linked to thrombosis. Disease-specific factors such as virus-induced endothelial changes and cytokine storm may also be triggers. Furthermore, patients with elevated …

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Hematology and OncologyInfectious DiseaseThoracic and Respiratory

REBEL Cast Book Club Episode 2 — The New Jim Crow

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Ketorolac for Acute MSK Pain: 15mg IM vs 60mg IM

The opioid epidemic has ignited a revolution in ED pain management over the last 5+ years. As such, opportunities for research have become more abundant and have driven ED pain management forward. Regional anesthesia, lidocaine infusions, intranasal ketamine, etc., are …

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Orthopedics

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